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- W2473832012 abstract "Background: Excised lungs expand asynchronously and nonuniformly during high frequency ventilation (Lehr 1985). Moreover, in healthy adults, pressure oscillations above 4 Hz applied at the mouth propagate inhomogeneously in the chest wall (Dellaca et al 2003). Objective: In newborn infants receiving HFOV, characterizing the regional heterogeneities of chest wall displacements at different oscillatory frequencies. Methods: We studied 14 newborns (gestational age=29±4 wks; postnatal age=7±8 days; body weight=1.2±0.7 Kg). The following frequencies were tested: 5, 8, 10, 12 and 15 Hz. For each frequency, the displacements of 24 passive markers placed on the infant9s chest wall were measured by optoelectronic plethysmography. A subset of 6 points were used to evaluate chest wall movements in the cranio-caudal direction. For each marker we computed: the displacement normalized for the ventilation pressure amplitude, the phase shift vs. mrk 1. Results: Pressure oscillations propagation decreased with frequency and was higher in the abdominal than in the ribcage compartment (Figure 1 left). The asynchrony of displacements in the cranio-caudal direction increases with f (Figure 1 right). Conclusion: In infants receiving HFOV the chest wall oscillates asynchronously and non-uniformly. With increasing frequency the pressure oscillations propagation reduces with frequency, while asynchronies become more evident." @default.
- W2473832012 created "2016-07-22" @default.
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- W2473832012 date "2015-09-01" @default.
- W2473832012 modified "2023-10-18" @default.
- W2473832012 title "Regional distribution of chest wall displacements in infants during high frequency oscillatory ventilation (HFOV)" @default.
- W2473832012 doi "https://doi.org/10.1183/13993003.congress-2015.pa1856" @default.
- W2473832012 hasPublicationYear "2015" @default.
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