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- W2474080552 abstract "Cryoballoon vs. Radiofrequency AF Ablation Introduction Radiofrequency (RF) and cryoballoon (CB) catheter ablation are effective for pulmonary vein isolation (PVI) in atrial fibrillation (AF). This report presents an updated meta‐analysis comparing the efficacy and safety of CB versus RF ablations in AF. Methods Databases and conference abstracts were systematically searched for studies that directly compared CB and RF PVI, and reported safety or efficacy outcomes in follow‐up ≥12 months. Recurrent atrial tachyarrhythmias (AT) were defined as AF, atrial flutter, or atrial tachycardia. Results Twenty‐two studies and 8,668 patients were included. Freedom from AT was not significantly different between CB and RF ablations in the pooled population (OR 1.12; 95%CI 0.97–1.29; P = 0.13) and in randomized trials (OR 1.0; 95%CI 0.65–1.56; P = 0.99). Second‐generation CB (CB2; 78.1%) and contact‐force (CF) sensing RF (78.2%) have improved procedure success rate as compared to first‐generation technology (57.9% CB, 58.1% RF). As compared to CF‐RF, CB2 demonstrated similar freedom from recurrent AT (OR 1.04; 95%CI 0.71–1.51; P = 0.84). The incidence of pericardial effusions (OR 0.44; 95%CI 0.28–0.69; P < 0.01), tamponade (OR 0.31; 95%CI 0.15–0.64; P < 0.01), and non‐AF AT (OR 0.46; 95%CI 0.26–0.83; P < 0.01) were significantly lower with CB ablation, whereas transient phrenic nerve palsy was more incident after CB (OR 7.40; 95%CI 2.56–21.34; P < 0.01). Conclusion There was comparable freedom from AT between CB and RF in patients with AF undergoing PVI. Additionally, freedom from AT was similar between CB2 and CF‐RF. However, CB was associated with a lower incidence of pericardial effusions or tamponade, albeit with a higher rate of transient phrenic nerve palsies." @default.
- W2474080552 created "2016-07-22" @default.
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- W2474080552 date "2016-08-16" @default.
- W2474080552 modified "2023-10-17" @default.
- W2474080552 title "Cryoballoon versus Radiofrequency Catheter Ablation in Atrial Fibrillation: A Meta-Analysis" @default.
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- W2474080552 doi "https://doi.org/10.1111/jce.13047" @default.
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