Matches in SemOpenAlex for { <https://semopenalex.org/work/W2474089345> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2474089345 endingPage "12" @default.
- W2474089345 startingPage "400" @default.
- W2474089345 abstract "The antilipolytic activity of nicotinic acid was investigated in 7 patients with type II b hyperlipoproteinemia and in 7 with type IV hyperlipoproteinemia treated for two months with a nicotinic acid derivative, sorbinicate (1600 mg daily, ie 1454 mg NA). Before and after treatment the blood levels of total cholesterol and triglycerides were determined and three dynamic tests -- oral glucose tolerance test, insulin test and tolbutamide test -- were done to check in each test the variations in blood glucose, NEFA, insulin (excluding obviously the insulin test), glucagon and growth hormone levels. At the end of the treatment, there was a significant reduction of cholesterol (type IIb and type IV) and of triglycerides (type IV), a marked reduction of the glucagon response, a slight increase in the insulin response and in the basal secretion of the growth hormone. It is suggested that the antilipolytic activity of nicotinic acid (and hence of sorbinicate) is at least partly mediated by an inhibition of glucagon secretion (and/or synthesis)." @default.
- W2474089345 created "2016-07-22" @default.
- W2474089345 creator A5009037399 @default.
- W2474089345 creator A5021480070 @default.
- W2474089345 creator A5076318425 @default.
- W2474089345 creator A5087711252 @default.
- W2474089345 date "1983-01-01" @default.
- W2474089345 modified "2023-09-23" @default.
- W2474089345 title "Possible glucagon-mediated hypocholesterolemic activity of a nicotinic acid derivative (sorbinicate)." @default.
- W2474089345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6661043" @default.
- W2474089345 hasPublicationYear "1983" @default.
- W2474089345 type Work @default.
- W2474089345 sameAs 2474089345 @default.
- W2474089345 citedByCount "1" @default.
- W2474089345 countsByYear W24740893452016 @default.
- W2474089345 crossrefType "journal-article" @default.
- W2474089345 hasAuthorship W2474089345A5009037399 @default.
- W2474089345 hasAuthorship W2474089345A5021480070 @default.
- W2474089345 hasAuthorship W2474089345A5076318425 @default.
- W2474089345 hasAuthorship W2474089345A5087711252 @default.
- W2474089345 hasConcept C126322002 @default.
- W2474089345 hasConcept C134018914 @default.
- W2474089345 hasConcept C170493617 @default.
- W2474089345 hasConcept C185592680 @default.
- W2474089345 hasConcept C188987157 @default.
- W2474089345 hasConcept C2776054734 @default.
- W2474089345 hasConcept C2778024521 @default.
- W2474089345 hasConcept C2778563252 @default.
- W2474089345 hasConcept C2779306644 @default.
- W2474089345 hasConcept C2779772378 @default.
- W2474089345 hasConcept C71315377 @default.
- W2474089345 hasConcept C71924100 @default.
- W2474089345 hasConceptScore W2474089345C126322002 @default.
- W2474089345 hasConceptScore W2474089345C134018914 @default.
- W2474089345 hasConceptScore W2474089345C170493617 @default.
- W2474089345 hasConceptScore W2474089345C185592680 @default.
- W2474089345 hasConceptScore W2474089345C188987157 @default.
- W2474089345 hasConceptScore W2474089345C2776054734 @default.
- W2474089345 hasConceptScore W2474089345C2778024521 @default.
- W2474089345 hasConceptScore W2474089345C2778563252 @default.
- W2474089345 hasConceptScore W2474089345C2779306644 @default.
- W2474089345 hasConceptScore W2474089345C2779772378 @default.
- W2474089345 hasConceptScore W2474089345C71315377 @default.
- W2474089345 hasConceptScore W2474089345C71924100 @default.
- W2474089345 hasIssue "5" @default.
- W2474089345 hasLocation W24740893451 @default.
- W2474089345 hasOpenAccess W2474089345 @default.
- W2474089345 hasPrimaryLocation W24740893451 @default.
- W2474089345 hasRelatedWork W1994456431 @default.
- W2474089345 hasRelatedWork W1996653633 @default.
- W2474089345 hasRelatedWork W2012327056 @default.
- W2474089345 hasRelatedWork W2015274285 @default.
- W2474089345 hasRelatedWork W2024609313 @default.
- W2474089345 hasRelatedWork W2026245542 @default.
- W2474089345 hasRelatedWork W2028467793 @default.
- W2474089345 hasRelatedWork W2032900229 @default.
- W2474089345 hasRelatedWork W2410507625 @default.
- W2474089345 hasRelatedWork W2417169713 @default.
- W2474089345 hasVolume "11" @default.
- W2474089345 isParatext "false" @default.
- W2474089345 isRetracted "false" @default.
- W2474089345 magId "2474089345" @default.
- W2474089345 workType "article" @default.