FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2474476139> ?p ?o ?g. }

• W2474476139 endingPage "e1004901" @default.
• W2474476139 startingPage "e1004901" @default.
• W2474476139 abstract "Infectious disease surveillance is key to limiting the consequences from infectious pathogens and maintaining animal and public health. Following the detection of a disease outbreak, a response in proportion to the severity of the outbreak is required. It is thus critical to obtain accurate information concerning the origin of the outbreak and its forward trajectory. However, there is often a lack of situational awareness that may lead to over- or under-reaction. There is a widening range of tests available for detecting pathogens, with typically different temporal characteristics, e.g. in terms of when peak test response occurs relative to time of exposure. We have developed a statistical framework that combines response level data from multiple diagnostic tests and is able to 'hindcast' (infer the historical trend of) an infectious disease epidemic. Assuming diagnostic test data from a cross-sectional sample of individuals infected with a pathogen during an outbreak, we use a Bayesian Markov Chain Monte Carlo (MCMC) approach to estimate time of exposure, and the overall epidemic trend in the population prior to the time of sampling. We evaluate the performance of this statistical framework on simulated data from epidemic trend curves and show that we can recover the parameter values of those trends. We also apply the framework to epidemic trend curves taken from two historical outbreaks: a bluetongue outbreak in cattle, and a whooping cough outbreak in humans. Together, these results show that hindcasting can estimate the time since infection for individuals and provide accurate estimates of epidemic trends, and can be used to distinguish whether an outbreak is increasing or past its peak. We conclude that if temporal characteristics of diagnostics are known, it is possible to recover epidemic trends of both human and animal pathogens from cross-sectional data collected at a single point in time." @default.
• W2474476139 created "2016-07-22" @default.
• W2474476139 creator A5019554063 @default.
• W2474476139 creator A5020699648 @default.
• W2474476139 creator A5026250128 @default.
• W2474476139 creator A5028354516 @default.
• W2474476139 creator A5053873381 @default.
• W2474476139 creator A5058727595 @default.
• W2474476139 creator A5068872863 @default.
• W2474476139 creator A5071022972 @default.
• W2474476139 creator A5072027356 @default.
• W2474476139 creator A5072811309 @default.
• W2474476139 date "2016-07-06" @default.
• W2474476139 modified "2023-09-29" @default.
• W2474476139 title "Using Combined Diagnostic Test Results to Hindcast Trends of Infection from Cross-Sectional Data" @default.
• W2474476139 cites W1536497620 @default.
• W2474476139 cites W1564419957 @default.
• W2474476139 cites W1963544842 @default.
• W2474476139 cites W1963614592 @default.
• W2474476139 cites W1965189574 @default.
• W2474476139 cites W1969907396 @default.
• W2474476139 cites W1971354053 @default.
• W2474476139 cites W1980099211 @default.
• W2474476139 cites W1985717369 @default.
• W2474476139 cites W1995093711 @default.
• W2474476139 cites W1996297484 @default.
• W2474476139 cites W2000153091 @default.
• W2474476139 cites W2000887190 @default.
• W2474476139 cites W2001449174 @default.
• W2474476139 cites W2014481041 @default.
• W2474476139 cites W2017977879 @default.
• W2474476139 cites W2023921293 @default.
• W2474476139 cites W2024029402 @default.
• W2474476139 cites W2028412780 @default.
• W2474476139 cites W2048105195 @default.
• W2474476139 cites W2048882309 @default.
• W2474476139 cites W2055041101 @default.
• W2474476139 cites W2055872303 @default.
• W2474476139 cites W2057477727 @default.
• W2474476139 cites W2059041686 @default.
• W2474476139 cites W2060405996 @default.
• W2474476139 cites W2061999635 @default.
• W2474476139 cites W2074190950 @default.
• W2474476139 cites W2074636365 @default.
• W2474476139 cites W2077333190 @default.
• W2474476139 cites W2080723129 @default.
• W2474476139 cites W2097158347 @default.
• W2474476139 cites W2098062910 @default.
• W2474476139 cites W2098446939 @default.
• W2474476139 cites W2102260676 @default.
• W2474476139 cites W2102940555 @default.
• W2474476139 cites W2105532502 @default.
• W2474476139 cites W2108198236 @default.
• W2474476139 cites W2108689970 @default.
• W2474476139 cites W2109885155 @default.
• W2474476139 cites W2115771275 @default.
• W2474476139 cites W2121009566 @default.
• W2474476139 cites W2137019479 @default.
• W2474476139 cites W2137203085 @default.
• W2474476139 cites W2143469080 @default.
• W2474476139 cites W2147851013 @default.
• W2474476139 cites W2152614795 @default.
• W2474476139 cites W2158606583 @default.
• W2474476139 cites W2159161166 @default.
• W2474476139 cites W2178385094 @default.
• W2474476139 cites W2260237638 @default.
• W2474476139 cites W2264709743 @default.
• W2474476139 doi "https://doi.org/10.1371/journal.pcbi.1004901" @default.
• W2474476139 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4934910" @default.
• W2474476139 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27384712" @default.
• W2474476139 hasPublicationYear "2016" @default.
• W2474476139 type Work @default.
• W2474476139 sameAs 2474476139 @default.
• W2474476139 citedByCount "15" @default.
• W2474476139 countsByYear W24744761392019 @default.
• W2474476139 countsByYear W24744761392020 @default.
• W2474476139 countsByYear W24744761392021 @default.
• W2474476139 countsByYear W24744761392022 @default.
• W2474476139 countsByYear W24744761392023 @default.
• W2474476139 crossrefType "journal-article" @default.
• W2474476139 hasAuthorship W2474476139A5019554063 @default.
• W2474476139 hasAuthorship W2474476139A5020699648 @default.
• W2474476139 hasAuthorship W2474476139A5026250128 @default.
• W2474476139 hasAuthorship W2474476139A5028354516 @default.
• W2474476139 hasAuthorship W2474476139A5053873381 @default.
• W2474476139 hasAuthorship W2474476139A5058727595 @default.
• W2474476139 hasAuthorship W2474476139A5068872863 @default.
• W2474476139 hasAuthorship W2474476139A5071022972 @default.
• W2474476139 hasAuthorship W2474476139A5072027356 @default.
• W2474476139 hasAuthorship W2474476139A5072811309 @default.
• W2474476139 hasBestOaLocation W24744761391 @default.
• W2474476139 hasConcept C105795698 @default.
• W2474476139 hasConcept C107673813 @default.
• W2474476139 hasConcept C111350023 @default.
• W2474476139 hasConcept C116675565 @default.
• W2474476139 hasConcept C119857082 @default.
• W2474476139 hasConcept C142724271 @default.
• W2474476139 hasConcept C159047783 @default.

• next