Matches in SemOpenAlex for { <https://semopenalex.org/work/W2474860104> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2474860104 endingPage "98" @default.
- W2474860104 startingPage "289" @default.
- W2474860104 abstract "Peptide YY (PYY) is a recently discovered polypeptide which has been proposed as physiological inhibitor of pancreatic exocrine secretion. The purpose of this study was to evaluate the effects of exogenous PYY on pancreatic blood flow and oxygen consumption. In anesthetized dogs, the superior pancreatico-duodenal artery blood flow (SPBF), pancreatic microcirculatory blood flow (PBF) and pancreatic oxygen consumption (PVO2) were determined. Control values for SPBF, PVO2 and PBF averaged 43.3 ml/min, 1.8 ml/min, and 57.5 ml/min/100g of tissue, respectively. Following iv injection of PYY at doses of 200 and 400 pmol/kg the values of SPBF decreased by 12 +/- 1% and 22 +/- 2%, respectively. PVO2 was reduced by those doses of PYY by 9 +/- 1 and 17 +/- 3%, respectively. PBF was also reduced by 16 +/- 2 and 34 +/- 2%, respectively after those doses of PYY. Pretreatment with phentolamine reversed the blood flow and PVO2 responses to PYY because SPBF, PVO2 and PBF were significantly increased above the control level. However, after additional pretreatment with propranolol the pancreatic vascular and metabolic responses to PYY were abolished. The above pancreatic responses to PYY were also significantly reduced after acute adrenalectomy. The experimental data indicate that adrenergic pathway is involved in the mechanism of action of PYY on the pancreatic circulation." @default.
- W2474860104 created "2016-07-22" @default.
- W2474860104 creator A5006735385 @default.
- W2474860104 creator A5028590412 @default.
- W2474860104 creator A5028649097 @default.
- W2474860104 creator A5031449923 @default.
- W2474860104 creator A5065427720 @default.
- W2474860104 creator A5069411919 @default.
- W2474860104 date "1992-05-01" @default.
- W2474860104 modified "2023-09-23" @default.
- W2474860104 title "Effects of peptide YY on pancreatic blood flow and oxygen consumption." @default.
- W2474860104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1470566" @default.
- W2474860104 hasPublicationYear "1992" @default.
- W2474860104 type Work @default.
- W2474860104 sameAs 2474860104 @default.
- W2474860104 citedByCount "0" @default.
- W2474860104 crossrefType "journal-article" @default.
- W2474860104 hasAuthorship W2474860104A5006735385 @default.
- W2474860104 hasAuthorship W2474860104A5028590412 @default.
- W2474860104 hasAuthorship W2474860104A5028649097 @default.
- W2474860104 hasAuthorship W2474860104A5031449923 @default.
- W2474860104 hasAuthorship W2474860104A5065427720 @default.
- W2474860104 hasAuthorship W2474860104A5069411919 @default.
- W2474860104 hasConcept C118303440 @default.
- W2474860104 hasConcept C126322002 @default.
- W2474860104 hasConcept C134018914 @default.
- W2474860104 hasConcept C158846371 @default.
- W2474860104 hasConcept C170493617 @default.
- W2474860104 hasConcept C185592680 @default.
- W2474860104 hasConcept C2780796126 @default.
- W2474860104 hasConcept C71924100 @default.
- W2474860104 hasConcept C93984277 @default.
- W2474860104 hasConceptScore W2474860104C118303440 @default.
- W2474860104 hasConceptScore W2474860104C126322002 @default.
- W2474860104 hasConceptScore W2474860104C134018914 @default.
- W2474860104 hasConceptScore W2474860104C158846371 @default.
- W2474860104 hasConceptScore W2474860104C170493617 @default.
- W2474860104 hasConceptScore W2474860104C185592680 @default.
- W2474860104 hasConceptScore W2474860104C2780796126 @default.
- W2474860104 hasConceptScore W2474860104C71924100 @default.
- W2474860104 hasConceptScore W2474860104C93984277 @default.
- W2474860104 hasIssue "3" @default.
- W2474860104 hasLocation W24748601041 @default.
- W2474860104 hasOpenAccess W2474860104 @default.
- W2474860104 hasPrimaryLocation W24748601041 @default.
- W2474860104 hasRelatedWork W1986199235 @default.
- W2474860104 hasRelatedWork W1996475372 @default.
- W2474860104 hasRelatedWork W2002569388 @default.
- W2474860104 hasRelatedWork W2005677996 @default.
- W2474860104 hasRelatedWork W2017562121 @default.
- W2474860104 hasRelatedWork W2059246703 @default.
- W2474860104 hasRelatedWork W2064185418 @default.
- W2474860104 hasRelatedWork W2065002129 @default.
- W2474860104 hasRelatedWork W2067446127 @default.
- W2474860104 hasRelatedWork W2162534744 @default.
- W2474860104 hasVolume "44" @default.
- W2474860104 isParatext "false" @default.
- W2474860104 isRetracted "false" @default.
- W2474860104 magId "2474860104" @default.
- W2474860104 workType "article" @default.