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- W2474869304 abstract "The effect of eight ethylenediamine and ethanolamine derivatives on inflammation was investigated in the carrageenan-induced rat paw edema model. The ability of these compounds to inhibit superoxide anion radical (O2-.) formation in vitro was also examined using the xanthine-xanthine oxidase system. Almost all of these substances were found to possess anti-inflammatory activity. This action can be well correlated with their reported capacity to inhibit microsomal membrane lipid peroxidation, while they demonstrated negligible effect on O2.- generation. The above actions appear to depend on some structural characteristics, particularly in the aromatic series of compounds." @default.
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- W2474869304 date "1992-11-01" @default.
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- W2474869304 title "Effect of some novel ethylenediamine and ethanolamine derivatives on carrageenan-induced inflammation. Correlation with antioxidant activity and structural characteristics." @default.
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