Matches in SemOpenAlex for { <https://semopenalex.org/work/W2474927405> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2474927405 abstract "Introduction : Myocardial ischemia is responsible of a high incidence of ischemic heart failure. Adjust experimental models of ischemic heart failure represents a help to improve our understanding in pathophysiology and to evaluate new medical or surgical therapies. In the present paper, we develop and characterize a pig model of ischemic and chronic heart failure. Methods: A fiameroid constrictor (3.5mm) is placed around the circumfl ex coronary artery and a second around the left descending coronary artery after a left thoracotomy in 21 pigs. Mortality rate is 57% at 2 months and 100% at 3 months. Angiocoronarography shows 90% stenosis as well as on the Cx and the LAD on surviving animals at 1 and 2 months. LV function is poor (30-35%) and associated with an important mitral valve insuffi ciency. Radial and circumference strains are dramatically modifi ed. Contrast echocardiography shows a signifi cant reduction in myocardial perfusion. Histogical analysis demonstrates no signifi cant differences in the capillary network in ischemic compared to non-ischemic area without demonstration of myocardial infarction. Conclusion: Despite a high rate of mortality, our fi nding suggest that we are able to create and to stabilize a chronic ischemic heart failure model in pig. This model represents a tool to develop new medical or surgical therapies in this domain." @default.
- W2474927405 created "2016-07-22" @default.
- W2474927405 creator A5002893978 @default.
- W2474927405 creator A5007806927 @default.
- W2474927405 creator A5037999616 @default.
- W2474927405 creator A5039106242 @default.
- W2474927405 creator A5044001061 @default.
- W2474927405 creator A5049203618 @default.
- W2474927405 creator A5073935034 @default.
- W2474927405 date "2009-01-01" @default.
- W2474927405 modified "2023-09-27" @default.
- W2474927405 title "Mise en place d'un modèle expérimental d'insuffi sance cardiaque ischémique chronique chez le porc" @default.
- W2474927405 cites W1722301188 @default.
- W2474927405 cites W1973837325 @default.
- W2474927405 cites W1975861963 @default.
- W2474927405 cites W2006981432 @default.
- W2474927405 cites W2017701060 @default.
- W2474927405 cites W2044571822 @default.
- W2474927405 cites W2050974735 @default.
- W2474927405 cites W2060255049 @default.
- W2474927405 cites W2071297987 @default.
- W2474927405 cites W2109712401 @default.
- W2474927405 cites W2132490702 @default.
- W2474927405 cites W2141077974 @default.
- W2474927405 cites W2146261185 @default.
- W2474927405 cites W2159762894 @default.
- W2474927405 cites W2159869836 @default.
- W2474927405 cites W2241120044 @default.
- W2474927405 cites W2356178343 @default.
- W2474927405 cites W2406707073 @default.
- W2474927405 cites W27554552 @default.
- W2474927405 hasPublicationYear "2009" @default.
- W2474927405 type Work @default.
- W2474927405 sameAs 2474927405 @default.
- W2474927405 citedByCount "0" @default.
- W2474927405 crossrefType "journal-article" @default.
- W2474927405 hasAuthorship W2474927405A5002893978 @default.
- W2474927405 hasAuthorship W2474927405A5007806927 @default.
- W2474927405 hasAuthorship W2474927405A5037999616 @default.
- W2474927405 hasAuthorship W2474927405A5039106242 @default.
- W2474927405 hasAuthorship W2474927405A5044001061 @default.
- W2474927405 hasAuthorship W2474927405A5049203618 @default.
- W2474927405 hasAuthorship W2474927405A5073935034 @default.
- W2474927405 hasConcept C126322002 @default.
- W2474927405 hasConcept C146957229 @default.
- W2474927405 hasConcept C164705383 @default.
- W2474927405 hasConcept C2776820930 @default.
- W2474927405 hasConcept C2778198053 @default.
- W2474927405 hasConcept C2778847313 @default.
- W2474927405 hasConcept C2780007028 @default.
- W2474927405 hasConcept C500558357 @default.
- W2474927405 hasConcept C541997718 @default.
- W2474927405 hasConcept C71924100 @default.
- W2474927405 hasConceptScore W2474927405C126322002 @default.
- W2474927405 hasConceptScore W2474927405C146957229 @default.
- W2474927405 hasConceptScore W2474927405C164705383 @default.
- W2474927405 hasConceptScore W2474927405C2776820930 @default.
- W2474927405 hasConceptScore W2474927405C2778198053 @default.
- W2474927405 hasConceptScore W2474927405C2778847313 @default.
- W2474927405 hasConceptScore W2474927405C2780007028 @default.
- W2474927405 hasConceptScore W2474927405C500558357 @default.
- W2474927405 hasConceptScore W2474927405C541997718 @default.
- W2474927405 hasConceptScore W2474927405C71924100 @default.
- W2474927405 hasLocation W24749274051 @default.
- W2474927405 hasOpenAccess W2474927405 @default.
- W2474927405 hasPrimaryLocation W24749274051 @default.
- W2474927405 isParatext "false" @default.
- W2474927405 isRetracted "false" @default.
- W2474927405 magId "2474927405" @default.
- W2474927405 workType "article" @default.