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- W2474934577 abstract "Summary Description of procedure Autologous chondrocyte transplantation (ACT) is a novel surgical approach used for the treatment of full thickness cartilage defects in knee joints. Small grafts of normal cartilage removed from a diseased joint are treated in a laboratory to obtain cartilage cells. These are cultured to expand the cell population and subsequently re-implanted, a few weeks later, into areas where cartilage is denuded. The aim of this procedure is to restore normal cartilage to the ends of bones and thereby restore normal joint function. This treatment is not funded by Health Authorities and is not routinely available although a few procedures have been carried out by a small number of surgeons. Epidemiology There are no reliable estimates of the prevalence of cartilage defects in the knee. Lesions are most likely to arise in sportsmen and women as a result of injury. Up to 20% of those sustaining a haemarthrosis following a knee injury may have cartilage damage. Number of studies and quality of evidence" @default.
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- W2474934577 date "2000-01-01" @default.
- W2474934577 modified "2023-09-24" @default.
- W2474934577 title "Autologous chondrocyte transplantation for cartilage defects in the knee joint A West Midlands Development and Evaluation Service Report" @default.
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