FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2474954920> ?p ?o ?g. }

• W2474954920 endingPage "78" @default.
• W2474954920 startingPage "159" @default.
• W2474954920 abstract "1. Clinical investigations at the University of Cincinnati have focused primarily on infection control, methods to increase donor-specific unresponsiveness, improvement in immunosuppression, donor maintenance and evaluation, posttransplant monitoring, and reduced-size livers for children. 2. Donor specific unresponsiveness (DSU) can be achieved frequently in recipients of both cadaver donor and living related donor kidneys by giving a single donor specific transfusion and CsA only 24 hours preoperatively with continuing triple immunosuppressive therapy. 3. Prednisone can be withdrawn from almost all patients with no rejection by 1 year with significant improvement in blood pressure, daily insulin requirement in diabetics, total blood cholesterol, and low density lipoproteins (LDL). 4. Oral ketoconazole 200 mg/day can be used safely to block the hepatic metabolism of CsA and reduce the amount of CsA administered by an average of 77-88%. This is of great economic consequence to lower income patients and patients with poor drug absorption. 5. Eighteen patients with SLE who received 23 kidney transplantations had an increase in graft loss in the first 6 months but the rate of graft loss after 6 months was almost identical to other ESRD patients. 6. The Cincinnati Transplant Tumor Registry has data on about 8,000 patients. Except for those with CNS tumors, patients with active cancers should not be used as donors. However, donors with previous curative procedures should not be excluded automatically. Cancers arising in immunosuppressed transplant recipients that have a higher incidence than the general population (expressed as percentage of treated cancers) are: lymphomas (22% vs 5%), lip cancers (7% vs 0.3%), Kaposi's sarcoma (6% vs less than 0.1%), vulva and perineal cancers (4% vs 0.6%), hepatobiliary cancers (2.5% vs 1.0%) and sarcomas (1.8% vs 0.5%). Other cancers have about the same-distribution. 7. Immunologic monitoring during OKT3 therapy is particularly useful in re-treatment and treatment of pediatric liver patients when increased doses of the drug may be necessary. 8. The MEGX test has been found to be a major predictor of primary non-function of the transplanted liver, and it is also useful in predicting the risks of dying from liver disease. 9. Reduced-size livers have been used in 37 patients, representing almost half of all pediatric liver transplants. Survival with reduced-size grafts (91% at 1 year) compared favorably with survival of whole organs (79% at 1 year). The benefit is particularly dramatic in infants with biliary atresia (100% 1-year graft survival in 24 patients, median age 11 months).(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W2474954920 created "2016-07-22" @default.
• W2474954920 creator A5009561448 @default.
• W2474954920 creator A5019836286 @default.
• W2474954920 creator A5032456775 @default.
• W2474954920 creator A5054724483 @default.
• W2474954920 creator A5055961830 @default.
• W2474954920 creator A5059078217 @default.
• W2474954920 creator A5079110708 @default.
• W2474954920 creator A5079197692 @default.
• W2474954920 creator A5087147218 @default.
• W2474954920 date "1991-01-01" @default.
• W2474954920 modified "2023-10-17" @default.
• W2474954920 title "Recent contributions to transplantation at the University of Cincinnati." @default.
• W2474954920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1820114" @default.
• W2474954920 hasPublicationYear "1991" @default.
• W2474954920 type Work @default.
• W2474954920 sameAs 2474954920 @default.
• W2474954920 citedByCount "2" @default.
• W2474954920 countsByYear W24749549202013 @default.
• W2474954920 crossrefType "journal-article" @default.
• W2474954920 hasAuthorship W2474954920A5009561448 @default.
• W2474954920 hasAuthorship W2474954920A5019836286 @default.
• W2474954920 hasAuthorship W2474954920A5032456775 @default.
• W2474954920 hasAuthorship W2474954920A5054724483 @default.
• W2474954920 hasAuthorship W2474954920A5055961830 @default.
• W2474954920 hasAuthorship W2474954920A5059078217 @default.
• W2474954920 hasAuthorship W2474954920A5079110708 @default.
• W2474954920 hasAuthorship W2474954920A5079197692 @default.
• W2474954920 hasAuthorship W2474954920A5087147218 @default.
• W2474954920 hasConcept C120665830 @default.
• W2474954920 hasConcept C121332964 @default.
• W2474954920 hasConcept C126322002 @default.
• W2474954920 hasConcept C126894567 @default.
• W2474954920 hasConcept C141071460 @default.
• W2474954920 hasConcept C2778720950 @default.
• W2474954920 hasConcept C2780014101 @default.
• W2474954920 hasConcept C2780252810 @default.
• W2474954920 hasConcept C2908647359 @default.
• W2474954920 hasConcept C2911091166 @default.
• W2474954920 hasConcept C61511704 @default.
• W2474954920 hasConcept C71924100 @default.
• W2474954920 hasConcept C90924648 @default.
• W2474954920 hasConcept C99454951 @default.
• W2474954920 hasConceptScore W2474954920C120665830 @default.
• W2474954920 hasConceptScore W2474954920C121332964 @default.
• W2474954920 hasConceptScore W2474954920C126322002 @default.
• W2474954920 hasConceptScore W2474954920C126894567 @default.
• W2474954920 hasConceptScore W2474954920C141071460 @default.
• W2474954920 hasConceptScore W2474954920C2778720950 @default.
• W2474954920 hasConceptScore W2474954920C2780014101 @default.
• W2474954920 hasConceptScore W2474954920C2780252810 @default.
• W2474954920 hasConceptScore W2474954920C2908647359 @default.
• W2474954920 hasConceptScore W2474954920C2911091166 @default.
• W2474954920 hasConceptScore W2474954920C61511704 @default.
• W2474954920 hasConceptScore W2474954920C71924100 @default.
• W2474954920 hasConceptScore W2474954920C90924648 @default.
• W2474954920 hasConceptScore W2474954920C99454951 @default.
• W2474954920 hasLocation W24749549201 @default.
• W2474954920 hasOpenAccess W2474954920 @default.
• W2474954920 hasPrimaryLocation W24749549201 @default.
• W2474954920 hasRelatedWork W1514256746 @default.
• W2474954920 hasRelatedWork W1969318433 @default.
• W2474954920 hasRelatedWork W2012436618 @default.
• W2474954920 hasRelatedWork W2080488192 @default.
• W2474954920 hasRelatedWork W2112002732 @default.
• W2474954920 hasRelatedWork W2147191983 @default.
• W2474954920 hasRelatedWork W2152029023 @default.
• W2474954920 hasRelatedWork W2316815868 @default.
• W2474954920 hasRelatedWork W2436485668 @default.
• W2474954920 hasRelatedWork W3150020355 @default.
• W2474954920 isParatext "false" @default.
• W2474954920 isRetracted "false" @default.
• W2474954920 magId "2474954920" @default.
• W2474954920 workType "article" @default.