Matches in SemOpenAlex for { <https://semopenalex.org/work/W2475050495> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2475050495 endingPage "82" @default.
- W2475050495 startingPage "377" @default.
- W2475050495 abstract "To investigate the effect of ethyl acetate extract from Chrysanthemum Morifolium Ramat (CME) on experimental arrhythmia induced by ischemia/reperfusion or aconitine in rats and to explore its underlying mechanisms.Arrhythmia model in intact rat was induced by aconitine (30 microg/kg body weight, i.v.). In isolated Langendorff perfused rat hearts, regional ischemia and reperfusion was induced by ligation and release of left anterior descending artery. The ventricular fibrillation threshold (VFT), effective refractory period (ERP), and diastolic excitation threshold (DET) in the isolated heart were measured. The action potentials of papillary muscle in rat right ventricle were recorded by conventional glass microelectrode technique.Compared with control group CME significantly decreased the number and duration of ventricular tachycardia (VT); delayed the occurrence of ventricular premature beats (VPB) and VT induced by aconitine. Arrhythmia score of the CME group was lower than that in aconitine-treated group. CME markedly prolonged the ERP and increased the VFT in the isolated perfused rat hearts during ischemia and reperfusion. CME prolonged action potential duration at 50% and 90% repolarization of the right ventricular papillary muscles and decreased the maximal rate of rise of the action potential upstroke, but did not affect the resting potential, amplitude of action potential.CME can reduce myocardial vulnerability and exerts its antiarrhythmic effects induced by aconitine or ischemia/reperfusion, which may be related to its prolongation of action potential duration and effective refractory period that enhance the electrophysiological stability of myocardiaium." @default.
- W2475050495 created "2016-07-22" @default.
- W2475050495 creator A5022534249 @default.
- W2475050495 creator A5025475304 @default.
- W2475050495 creator A5036341624 @default.
- W2475050495 creator A5042504889 @default.
- W2475050495 creator A5052813888 @default.
- W2475050495 creator A5065428996 @default.
- W2475050495 creator A5067857559 @default.
- W2475050495 creator A5085030237 @default.
- W2475050495 creator A5085075008 @default.
- W2475050495 date "2009-07-01" @default.
- W2475050495 modified "2023-09-26" @default.
- W2475050495 title "[Antiarrhythmic effect of ethyl acetate extract from Chrysanthemum Morifolium Ramat on rats]." @default.
- W2475050495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19693975" @default.
- W2475050495 hasPublicationYear "2009" @default.
- W2475050495 type Work @default.
- W2475050495 sameAs 2475050495 @default.
- W2475050495 citedByCount "1" @default.
- W2475050495 crossrefType "journal-article" @default.
- W2475050495 hasAuthorship W2475050495A5022534249 @default.
- W2475050495 hasAuthorship W2475050495A5025475304 @default.
- W2475050495 hasAuthorship W2475050495A5036341624 @default.
- W2475050495 hasAuthorship W2475050495A5042504889 @default.
- W2475050495 hasAuthorship W2475050495A5052813888 @default.
- W2475050495 hasAuthorship W2475050495A5065428996 @default.
- W2475050495 hasAuthorship W2475050495A5067857559 @default.
- W2475050495 hasAuthorship W2475050495A5085030237 @default.
- W2475050495 hasAuthorship W2475050495A5085075008 @default.
- W2475050495 hasConcept C126322002 @default.
- W2475050495 hasConcept C146403970 @default.
- W2475050495 hasConcept C164705383 @default.
- W2475050495 hasConcept C185263204 @default.
- W2475050495 hasConcept C189327125 @default.
- W2475050495 hasConcept C2776331378 @default.
- W2475050495 hasConcept C2777274916 @default.
- W2475050495 hasConcept C2777547430 @default.
- W2475050495 hasConcept C2778921608 @default.
- W2475050495 hasConcept C2781005686 @default.
- W2475050495 hasConcept C42219234 @default.
- W2475050495 hasConcept C541997718 @default.
- W2475050495 hasConcept C70616116 @default.
- W2475050495 hasConcept C71924100 @default.
- W2475050495 hasConcept C98274493 @default.
- W2475050495 hasConceptScore W2475050495C126322002 @default.
- W2475050495 hasConceptScore W2475050495C146403970 @default.
- W2475050495 hasConceptScore W2475050495C164705383 @default.
- W2475050495 hasConceptScore W2475050495C185263204 @default.
- W2475050495 hasConceptScore W2475050495C189327125 @default.
- W2475050495 hasConceptScore W2475050495C2776331378 @default.
- W2475050495 hasConceptScore W2475050495C2777274916 @default.
- W2475050495 hasConceptScore W2475050495C2777547430 @default.
- W2475050495 hasConceptScore W2475050495C2778921608 @default.
- W2475050495 hasConceptScore W2475050495C2781005686 @default.
- W2475050495 hasConceptScore W2475050495C42219234 @default.
- W2475050495 hasConceptScore W2475050495C541997718 @default.
- W2475050495 hasConceptScore W2475050495C70616116 @default.
- W2475050495 hasConceptScore W2475050495C71924100 @default.
- W2475050495 hasConceptScore W2475050495C98274493 @default.
- W2475050495 hasIssue "4" @default.
- W2475050495 hasLocation W24750504951 @default.
- W2475050495 hasOpenAccess W2475050495 @default.
- W2475050495 hasPrimaryLocation W24750504951 @default.
- W2475050495 hasRelatedWork W2044531713 @default.
- W2475050495 hasRelatedWork W2071521299 @default.
- W2475050495 hasRelatedWork W2091682985 @default.
- W2475050495 hasRelatedWork W2374949814 @default.
- W2475050495 hasRelatedWork W2391317193 @default.
- W2475050495 hasRelatedWork W2393017609 @default.
- W2475050495 hasRelatedWork W2419109141 @default.
- W2475050495 hasRelatedWork W2475050495 @default.
- W2475050495 hasRelatedWork W4280636489 @default.
- W2475050495 hasRelatedWork W1998572690 @default.
- W2475050495 hasVolume "38" @default.
- W2475050495 isParatext "false" @default.
- W2475050495 isRetracted "false" @default.
- W2475050495 magId "2475050495" @default.
- W2475050495 workType "article" @default.