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- W2475060157 startingPage "1971" @default.
- W2475060157 abstract "Evidence suggests the existence of a Na,K-ATPase inhibitor, so called endogenous digitalis-like factor (EDLF), in plasma. This substance has been postulated to enhance renal tubular sodium excretion and to increase peripheral vascular resistance. Recently, plant ouabain or its isomer (ouabain-like compound, OLC) was purified from human plasma and bovine hypothalamic extract. The OLC is considered to be a candidate for the EDLF. The OLC has been implicated in the pathogenesis of sodium-dependent hypertension. Furthermore, accumulating evidence suggests central nervous system as a site of hypertensinogenic action of OLC." @default.
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- W2475060157 date "1997-08-01" @default.
- W2475060157 modified "2023-09-23" @default.
- W2475060157 title "[Endogenous digitalis-like factor]." @default.
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