FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2475146539> ?p ?o ?g. }

• W2475146539 endingPage "16" @default.
• W2475146539 startingPage "1" @default.
• W2475146539 abstract "There is a large diversity of oligosaccharide sequences linked to proteins. The molecules classically called glycoproteins comprise serum and cell membrane glycoproteins of approximate mol-wt range 20–200 kDa, having oligosaccharide chains linked to Ser/Thr or Asn, i.e., O- and N-linked, respectively, making up between 10 and 60% by weight. The structures of these chains are introduced in Chapters 2 – 12 of this book and the variety of glycosylation assessed in the Glossary. Additionally covered are (1) mucins, which are traditionally defined as larger mol-wt glycoproteins of 106 kDa and upwards having >60% oligosaccharide, mainly O-linked via GalNAc-containing oligosaccharide cores, and (2) proteoglycans or glycosaminoglycans, which also have a high carbohydrate/protein ratio, but classically have disaccharide repeating units with an alternate uronic acid residue and a large degree of sulfation. The distinction between these categories is becoming increasingly blurred, and they can now be seen as a spectrum of the aforementioned glycosylation patterns occurring on high- and low-mol-wt, secreted, and cell-surface glycoproteins. As examples of this diversity, classical mucin and proteoglycan sequences can occur on cell-membrane-attached proteins of relatively low mol-wt (1); glycoproteins and proteoglycans are found in forms attached to the membrane by lipid-linked anchors (ref. 1 and Chapter 8 ), and cytoplasmic glycoproteins having GlcNAc linked to Ser and Thr (ref. 2 and Chapter 14 ) are now also known. Additional oligosaccharide-to-protein linkages are found in proteoglycans (1) and bacterial glycoproteins (ref. 3 and Chapter 9 ). Because of the variety of glycoproteins, monosaccharides, and their derivatives found in nature, the assessment of glycosylation status of a protein, requires four levels of questioning." @default.
• W2475146539 created "2016-07-22" @default.
• W2475146539 creator A5015874787 @default.
• W2475146539 date "2003-11-14" @default.
• W2475146539 modified "2023-09-25" @default.
• W2475146539 title "A General Strategy for Glycoprotein Oligosaccharide Analysis" @default.
• W2475146539 cites W2008293119 @default.
• W2475146539 cites W2055090102 @default.
• W2475146539 cites W2098502201 @default.
• W2475146539 cites W2155745520 @default.
• W2475146539 cites W2415961012 @default.
• W2475146539 cites W935349725 @default.
• W2475146539 doi "https://doi.org/10.1385/0-89603-226-4:1" @default.
• W2475146539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8348227" @default.
• W2475146539 hasPublicationYear "2003" @default.
• W2475146539 type Work @default.
• W2475146539 sameAs 2475146539 @default.
• W2475146539 citedByCount "11" @default.
• W2475146539 crossrefType "book-chapter" @default.
• W2475146539 hasAuthorship W2475146539A5015874787 @default.
• W2475146539 hasConcept C108625454 @default.
• W2475146539 hasConcept C179264091 @default.
• W2475146539 hasConcept C185592680 @default.
• W2475146539 hasConcept C206212055 @default.
• W2475146539 hasConcept C2777313579 @default.
• W2475146539 hasConcept C2777459641 @default.
• W2475146539 hasConcept C2777726330 @default.
• W2475146539 hasConcept C55493867 @default.
• W2475146539 hasConceptScore W2475146539C108625454 @default.
• W2475146539 hasConceptScore W2475146539C179264091 @default.
• W2475146539 hasConceptScore W2475146539C185592680 @default.
• W2475146539 hasConceptScore W2475146539C206212055 @default.
• W2475146539 hasConceptScore W2475146539C2777313579 @default.
• W2475146539 hasConceptScore W2475146539C2777459641 @default.
• W2475146539 hasConceptScore W2475146539C2777726330 @default.
• W2475146539 hasConceptScore W2475146539C55493867 @default.
• W2475146539 hasLocation W24751465391 @default.
• W2475146539 hasLocation W24751465392 @default.
• W2475146539 hasOpenAccess W2475146539 @default.
• W2475146539 hasPrimaryLocation W24751465391 @default.
• W2475146539 hasRelatedWork W1594263740 @default.
• W2475146539 hasRelatedWork W1693086232 @default.
• W2475146539 hasRelatedWork W1981905369 @default.
• W2475146539 hasRelatedWork W1987290897 @default.
• W2475146539 hasRelatedWork W2003371133 @default.
• W2475146539 hasRelatedWork W2118002029 @default.
• W2475146539 hasRelatedWork W2168282690 @default.
• W2475146539 hasRelatedWork W2413039978 @default.
• W2475146539 hasRelatedWork W2475146539 @default.
• W2475146539 hasRelatedWork W4285201588 @default.
• W2475146539 isParatext "false" @default.
• W2475146539 isRetracted "false" @default.
• W2475146539 magId "2475146539" @default.
• W2475146539 workType "book-chapter" @default.