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- W2475262862 abstract "This case report describes the treatment of a patient with end-stage renal disease on peritoneal dialysis who presented with triglycerides of 35 mmol/l, cholesterol of 14 mmol/l and visible chylomicronaemia. She was only partially responsive to statin and fibrate monotherapy, so was treated with fibrate-statin combination therapy. Daily fibrate therapy resulted in a myositis, but once-weekly fibrate therapy with nocturnal daily statin therapy resulted in a reduction in total cholesterol of 49%, triglycerides of 82% and raised HDL by 52%, enabling her to achieve a target LDL of 3 mmol/l and HDL of 1 mmol/l. Combination therapy with low frequency (weekly) fibrate administration and daily statin treatment may provide a means to control the severe hypertriglyceridaemia of patients with renal disease." @default.
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- W2475262862 date "2003-04-01" @default.
- W2475262862 modified "2023-09-26" @default.
- W2475262862 title "COMBINATION FIB RATE‐STATIN THERAPY FOR THE TREATMENT OF SEVERE HYPERTRIGLYCERIDAEMIA IN RENAL DISEASE" @default.
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- W2475262862 doi "https://doi.org/10.1111/j.1742-1241.2003.tb10476.x" @default.
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