Matches in SemOpenAlex for { <https://semopenalex.org/work/W2475497860> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2475497860 abstract "A duodenal levodopa (L-dopa) and carbidopa infusion has been developed to stabilize plasma levels of L-dopa, in order to reduce existing motor response fluctuations. Stable plasma levels have been shown to reduce these fluctuations significantly. A constant duodenal infusion with an L-dopa solution can improve response fluctuations, however L-dopa has very poor solubility. Only in an acidic environment can L-dopa be dissolved in large volumes. To supply 1 day of infusion with the conventional L-dopa solution, ∼4–5 liters are necessary, an inconvenience to most patients. With L-dopa/carbidopa infusion, L-dopa and carbidopa are concentrated in a water-based gel-like suspension to 20 mg/mL, which has reduced the infusion volumes to <100 mL/day." @default.
- W2475497860 created "2016-08-23" @default.
- W2475497860 creator A5015826135 @default.
- W2475497860 creator A5084905530 @default.
- W2475497860 date "2008-04-01" @default.
- W2475497860 modified "2023-09-26" @default.
- W2475497860 title "Continuous Drug Delivery with Levodopa/Carbidopa Infusion: Review and First Data of a Dutch Cohort" @default.
- W2475497860 cites W1969522203 @default.
- W2475497860 cites W1985133850 @default.
- W2475497860 cites W2011418698 @default.
- W2475497860 cites W2026246620 @default.
- W2475497860 cites W2061469930 @default.
- W2475497860 cites W2092105200 @default.
- W2475497860 cites W2135640360 @default.
- W2475497860 cites W2165307652 @default.
- W2475497860 doi "https://doi.org/10.1017/s1092852900017363" @default.
- W2475497860 hasPublicationYear "2008" @default.
- W2475497860 type Work @default.
- W2475497860 sameAs 2475497860 @default.
- W2475497860 citedByCount "0" @default.
- W2475497860 crossrefType "journal-article" @default.
- W2475497860 hasAuthorship W2475497860A5015826135 @default.
- W2475497860 hasAuthorship W2475497860A5084905530 @default.
- W2475497860 hasConcept C126322002 @default.
- W2475497860 hasConcept C2776754145 @default.
- W2475497860 hasConcept C2779134260 @default.
- W2475497860 hasConcept C2779734285 @default.
- W2475497860 hasConcept C2780035454 @default.
- W2475497860 hasConcept C2780304432 @default.
- W2475497860 hasConcept C71924100 @default.
- W2475497860 hasConcept C72563966 @default.
- W2475497860 hasConcept C98274493 @default.
- W2475497860 hasConceptScore W2475497860C126322002 @default.
- W2475497860 hasConceptScore W2475497860C2776754145 @default.
- W2475497860 hasConceptScore W2475497860C2779134260 @default.
- W2475497860 hasConceptScore W2475497860C2779734285 @default.
- W2475497860 hasConceptScore W2475497860C2780035454 @default.
- W2475497860 hasConceptScore W2475497860C2780304432 @default.
- W2475497860 hasConceptScore W2475497860C71924100 @default.
- W2475497860 hasConceptScore W2475497860C72563966 @default.
- W2475497860 hasConceptScore W2475497860C98274493 @default.
- W2475497860 hasLocation W24754978601 @default.
- W2475497860 hasOpenAccess W2475497860 @default.
- W2475497860 hasPrimaryLocation W24754978601 @default.
- W2475497860 hasRelatedWork W1854249869 @default.
- W2475497860 hasRelatedWork W1991538916 @default.
- W2475497860 hasRelatedWork W2020950927 @default.
- W2475497860 hasRelatedWork W2051315202 @default.
- W2475497860 hasRelatedWork W2085233739 @default.
- W2475497860 hasRelatedWork W2179862831 @default.
- W2475497860 hasRelatedWork W2287525020 @default.
- W2475497860 hasRelatedWork W2409078984 @default.
- W2475497860 hasRelatedWork W2410579593 @default.
- W2475497860 hasRelatedWork W2567114989 @default.
- W2475497860 hasRelatedWork W2791787092 @default.
- W2475497860 hasRelatedWork W2914468735 @default.
- W2475497860 hasRelatedWork W2921995975 @default.
- W2475497860 hasRelatedWork W2978503476 @default.
- W2475497860 hasRelatedWork W2980354621 @default.
- W2475497860 hasRelatedWork W3001578918 @default.
- W2475497860 hasRelatedWork W3016735600 @default.
- W2475497860 hasRelatedWork W3098689962 @default.
- W2475497860 hasRelatedWork W41970388 @default.
- W2475497860 hasRelatedWork W67935638 @default.
- W2475497860 isParatext "false" @default.
- W2475497860 isRetracted "false" @default.
- W2475497860 magId "2475497860" @default.
- W2475497860 workType "article" @default.