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- W2475509753 abstract "Dipalmitoylphosphatidylcholine (DPPC) vesicles in aqueous buffer, prepared by sonication and controlled fusion, were characterized by differential scanning calorimetry (DSC) analysis. Size variations in vesicle preparations during fusion were analyzed by spectroturbidity measurements and laser scattering analysis. Inasmuch as the measured turbidity of a vesicle preparation was shown to be directly proportional to the concentration of the phospholipid in the vesicled form, the relative quantity of vesicles remaining after applying a drying and rehydration procedure was estimated from turbidity measurements taken before and after drying. A parameter, ηR, the rehydration efficiency, was defined in terms of turbidity changes to express the resilience of vesicles to the drying-induced stress. Values of ηR were determined for vesicles dried and rehydrated in the presence of candidate preservatives, including carbohydrates and metal ions. Disaccharides stabilized dried phospholipid vesicles better than monosaccharides; polyols were destabilizing at all studied concentrations, and metal ions were mildly stabilizing only at low concentrations. Extracts of milk fat globules (MFG) from whole milk were analyzed for their resilience toward drying-induced rupture in the absence and presence of candidate preservatives by the spectroturbidimetric method. Of the studied additives, maltodextrin M-100 (a hydrolyzed corn starch) was found to be the most effective stabilizer. Analogous studies of dried diluted whole milk samples, in which the major contributor to sample turbidity was due to the component MFGs, indicated that the best single stabilizing additive toward drying-induced rupture of MFGs is maltodextrin M-100." @default.
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- W2475509753 date "1991-12-26" @default.
- W2475509753 modified "2023-09-25" @default.
- W2475509753 title "Evaluation of Stabilizers for Synthetic Vesicles and Milk Fat Globules under Drying Stress" @default.
- W2475509753 doi "https://doi.org/10.1021/bk-1991-0448.ch013" @default.
- W2475509753 hasPublicationYear "1991" @default.
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