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- W2475599013 abstract "This chapter provides a brief overview of the nervous system, highlighting some of the factors contributing to its unique sensitivity towards chemical warfare agents (CWAs). Neurotoxicants are any chemical agents that disrupt the normal function of the nervous system, in the presence or absence of visible structural damage. The first category of neurotoxicants results in a neuronopathy or death of a neuron, with subsequent degeneration of its associated axon, dendrites, and myelin sheath when present. The second category of neurotoxicants results in the loss of axons that later can include the degeneration of all associated myelin sheaths. Many of the different types of CWAs can elicit neurotoxic responses. In some cases, these neurotoxic effects are elicited by direct interaction with specific target molecules within the nervous system, while in other cases the target is less specific but the tissue itself is more sensitive, and in yet other cases actions on other organ systems can lead to indirect impairment of neurologic function. Thus, knowledge of mechanisms of neurotoxicity for CWAs can aid in understanding how to counteract such adverse neurological effects." @default.
- W2475599013 created "2016-08-23" @default.
- W2475599013 creator A5008410537 @default.
- W2475599013 creator A5039314139 @default.
- W2475599013 creator A5041676888 @default.
- W2475599013 date "2009-01-01" @default.
- W2475599013 modified "2023-09-27" @default.
- W2475599013 title "The Nervous System as a Target for Chemical Warfare Agents" @default.
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