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- W2476366083 abstract "Many regulatory peptides have been described in the respiratory tract of animals and humans. Some peptides (bombesin, calcitonin, calcitonin gene-related peptide) are localised to neuroendocrine cells and may have a trophic or transmitter role. Others are localised to motor nerves. Vasoactive intestinal peptide and peptide histidine isoleucine are candidates for neurotransmitters of non-adrenergic inhibitory fibres and may be co-transmitters in cholinergic nerves. These peptides may regulate airway smooth muscle tone, bronchial blood flow and airway secretions. Sensory neuropeptides (substance P, neurokinin A and B, calcitonin gene-related peptide) may contract airway smooth muscle, stimulate mucus secretion and regulate bronchial blood flow and microvascular permeability. If released by an axon reflex mechanism these peptides may be involved in the pathogenesis of asthma. Other peptides, such as galanin and neuropeptide Y, are also present but their function is not yet known." @default.
- W2476366083 created "2016-08-23" @default.
- W2476366083 creator A5007877190 @default.
- W2476366083 date "1989-01-01" @default.
- W2476366083 modified "2023-09-25" @default.
- W2476366083 title "Regulatory peptides in the respiratory system" @default.
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- W2476366083 doi "https://doi.org/10.1007/978-3-0348-9136-3_17" @default.
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