Matches in SemOpenAlex for { <https://semopenalex.org/work/W2476491197> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2476491197 abstract "Introduction: Thalassemia is a genetic inherited blood disorder in which the body makes abnormal hemoglobin with excessive destruction of red blood cells, which leads to anemia. For many years, hepatitis B virus was a major problem for patients with thalassemia substantially contracted from blood transfusions. The development of effective vaccine has further reduced the magnitude of the problem of hepatitis B. Iron chelators are used to remove excess iron that accumulates due to repeated blood transfusion.Aim of the work: To compare thalassemic patients either have or haven’t HCV with healthy persons as regards biochemical indices taking in consideration effect of vaccination against HBV or not and using iron chelating therapy or not by the studied persons.Methodology: A case control study in which 40 thalassemic, blood transfusion dependent patients were chosen randomly to act as a case group from thalassemic patients attending the VACSERA Company. The cases (40 patients) they were classified to patients having HCV, patients were HBV vaccinated ,other non vaccinated, using iron chelating therapyor don’t use it. Another 10 healthy and non thalassemic persons were chosen randomly among persons attending the same company as a control group to be matched with the case group.Results: 50% of studied thalassemic patients had HCV seropositivity. Biochemical blood indices which were found to be significantly elevated among thalassemic patients than controls were ALT, AST, ALP, GGT and LDH enzymes in addition to serum iron, ferritin and globulin mostly in HBV non-vaccinated and iron chelating therapy non dependent patients while, other biochemical indices which were significantly decreased among thalassemic patients compared to controls included: total cholesterol, total protein, albumin and albumin/globulin ratio mostly in HBV vaccinated and iron chelating non dependent patients.Conclusion: this study illustrated the effectiveness of iron chelators agentsand the importance of vaccination for reduction of morbidity and mortality." @default.
- W2476491197 created "2016-08-23" @default.
- W2476491197 creator A5003050741 @default.
- W2476491197 creator A5003166214 @default.
- W2476491197 creator A5039881825 @default.
- W2476491197 creator A5041000944 @default.
- W2476491197 creator A5072141005 @default.
- W2476491197 date "2014-10-01" @default.
- W2476491197 modified "2023-09-27" @default.
- W2476491197 title "Effects of Iron Chelating Therapy and / or HBV - Vaccination on β-Thalassemia Major Patients" @default.
- W2476491197 cites W13717313 @default.
- W2476491197 cites W1493314259 @default.
- W2476491197 cites W1520200793 @default.
- W2476491197 cites W1791272576 @default.
- W2476491197 cites W1901351590 @default.
- W2476491197 cites W1967354181 @default.
- W2476491197 cites W1986677646 @default.
- W2476491197 cites W2019525497 @default.
- W2476491197 cites W2032313248 @default.
- W2476491197 cites W2060664419 @default.
- W2476491197 cites W2063620744 @default.
- W2476491197 cites W2083522890 @default.
- W2476491197 cites W2089876393 @default.
- W2476491197 cites W2099163399 @default.
- W2476491197 cites W2102855662 @default.
- W2476491197 cites W2103655963 @default.
- W2476491197 cites W2112154893 @default.
- W2476491197 cites W2118236060 @default.
- W2476491197 cites W2120271642 @default.
- W2476491197 cites W2132333179 @default.
- W2476491197 cites W2166561415 @default.
- W2476491197 cites W2167575052 @default.
- W2476491197 cites W2299218429 @default.
- W2476491197 cites W2462014695 @default.
- W2476491197 doi "https://doi.org/10.12816/0008483" @default.
- W2476491197 hasPublicationYear "2014" @default.
- W2476491197 type Work @default.
- W2476491197 sameAs 2476491197 @default.
- W2476491197 citedByCount "0" @default.
- W2476491197 crossrefType "journal-article" @default.
- W2476491197 hasAuthorship W2476491197A5003050741 @default.
- W2476491197 hasAuthorship W2476491197A5003166214 @default.
- W2476491197 hasAuthorship W2476491197A5039881825 @default.
- W2476491197 hasAuthorship W2476491197A5041000944 @default.
- W2476491197 hasAuthorship W2476491197A5072141005 @default.
- W2476491197 hasConcept C126322002 @default.
- W2476491197 hasConcept C203014093 @default.
- W2476491197 hasConcept C22070199 @default.
- W2476491197 hasConcept C2776517179 @default.
- W2476491197 hasConcept C2777218474 @default.
- W2476491197 hasConcept C2777382497 @default.
- W2476491197 hasConcept C2777799968 @default.
- W2476491197 hasConcept C2778248108 @default.
- W2476491197 hasConcept C2778319317 @default.
- W2476491197 hasConcept C2778917026 @default.
- W2476491197 hasConcept C2780014101 @default.
- W2476491197 hasConcept C71924100 @default.
- W2476491197 hasConcept C90924648 @default.
- W2476491197 hasConceptScore W2476491197C126322002 @default.
- W2476491197 hasConceptScore W2476491197C203014093 @default.
- W2476491197 hasConceptScore W2476491197C22070199 @default.
- W2476491197 hasConceptScore W2476491197C2776517179 @default.
- W2476491197 hasConceptScore W2476491197C2777218474 @default.
- W2476491197 hasConceptScore W2476491197C2777382497 @default.
- W2476491197 hasConceptScore W2476491197C2777799968 @default.
- W2476491197 hasConceptScore W2476491197C2778248108 @default.
- W2476491197 hasConceptScore W2476491197C2778319317 @default.
- W2476491197 hasConceptScore W2476491197C2778917026 @default.
- W2476491197 hasConceptScore W2476491197C2780014101 @default.
- W2476491197 hasConceptScore W2476491197C71924100 @default.
- W2476491197 hasConceptScore W2476491197C90924648 @default.
- W2476491197 hasLocation W24764911971 @default.
- W2476491197 hasOpenAccess W2476491197 @default.
- W2476491197 hasPrimaryLocation W24764911971 @default.
- W2476491197 hasRelatedWork W2079493559 @default.
- W2476491197 hasRelatedWork W2106811759 @default.
- W2476491197 hasRelatedWork W2139608858 @default.
- W2476491197 hasRelatedWork W2140198456 @default.
- W2476491197 hasRelatedWork W2271264844 @default.
- W2476491197 hasRelatedWork W2282949830 @default.
- W2476491197 hasRelatedWork W2519136086 @default.
- W2476491197 hasRelatedWork W2611788051 @default.
- W2476491197 hasRelatedWork W2962995770 @default.
- W2476491197 hasRelatedWork W3039063472 @default.
- W2476491197 hasRelatedWork W3083711174 @default.
- W2476491197 hasRelatedWork W3097807201 @default.
- W2476491197 hasRelatedWork W3137716140 @default.
- W2476491197 hasRelatedWork W2186626483 @default.
- W2476491197 hasRelatedWork W2189574026 @default.
- W2476491197 hasRelatedWork W2307933051 @default.
- W2476491197 hasRelatedWork W2510861912 @default.
- W2476491197 hasRelatedWork W3119136269 @default.
- W2476491197 hasRelatedWork W41250224 @default.
- W2476491197 hasRelatedWork W96968825 @default.
- W2476491197 isParatext "false" @default.
- W2476491197 isRetracted "false" @default.
- W2476491197 magId "2476491197" @default.
- W2476491197 workType "article" @default.