Matches in SemOpenAlex for { <https://semopenalex.org/work/W2478009671> ?p ?o ?g. }
- W2478009671 endingPage "129" @default.
- W2478009671 startingPage "119" @default.
- W2478009671 abstract "This chapter discusses the development of fluid transport across the pulmonary epithelia. In the fetus, active secretion of Cl across both airway and alveolar epithelia drives water into the lung, and the resulting elevation of intraluminal hydrostatic pressure is essential important for normal lung development. However, at the time of birth, the primary type of active solute transport across pulmonary epithelia switches, within minutes, from active secretion of Cl– to active absorption of Na+. The transepithelial osmotic gradients are reversed and luminal liquid is absorbed as the lungs fill with air. This switch is affected by the interplay of a number of hormones of which the ultimate is usually epinephrine. Changes in arterial O2 tension and in the extracellular matrix help maintain liquid absorption. The perinatal increase in Na absorption is initially due to insertion of ENaC into the apical membrane, followed later by an increase in the numbers of Na-K-ATPase on the basolateral membrane. The perinatal decrease in active Cl secretion is probably mainly due to a change in apical membrane potential difference consequent on increased Na conductance." @default.
- W2478009671 created "2016-08-23" @default.
- W2478009671 creator A5026572261 @default.
- W2478009671 date "2004-01-01" @default.
- W2478009671 modified "2023-10-16" @default.
- W2478009671 title "Development of Fluid Transport Pulmonary Epithelia" @default.
- W2478009671 cites W113698564 @default.
- W2478009671 cites W1483167918 @default.
- W2478009671 cites W1607565236 @default.
- W2478009671 cites W1758963015 @default.
- W2478009671 cites W1811888932 @default.
- W2478009671 cites W1815140768 @default.
- W2478009671 cites W1890896653 @default.
- W2478009671 cites W1924988649 @default.
- W2478009671 cites W1963628222 @default.
- W2478009671 cites W1964584239 @default.
- W2478009671 cites W1986612168 @default.
- W2478009671 cites W1988360505 @default.
- W2478009671 cites W1995327372 @default.
- W2478009671 cites W2001172655 @default.
- W2478009671 cites W2002565017 @default.
- W2478009671 cites W2003287070 @default.
- W2478009671 cites W2009565299 @default.
- W2478009671 cites W2011042737 @default.
- W2478009671 cites W2012294885 @default.
- W2478009671 cites W2012329129 @default.
- W2478009671 cites W2013339694 @default.
- W2478009671 cites W2013725292 @default.
- W2478009671 cites W2014359221 @default.
- W2478009671 cites W2016235368 @default.
- W2478009671 cites W2020814457 @default.
- W2478009671 cites W2022479952 @default.
- W2478009671 cites W2023804289 @default.
- W2478009671 cites W2024107440 @default.
- W2478009671 cites W2025614075 @default.
- W2478009671 cites W2030191770 @default.
- W2478009671 cites W2030374599 @default.
- W2478009671 cites W2033269270 @default.
- W2478009671 cites W2033976875 @default.
- W2478009671 cites W2051766330 @default.
- W2478009671 cites W2052207864 @default.
- W2478009671 cites W2052763452 @default.
- W2478009671 cites W2055466685 @default.
- W2478009671 cites W2060494176 @default.
- W2478009671 cites W2063403431 @default.
- W2478009671 cites W2064654478 @default.
- W2478009671 cites W2065729941 @default.
- W2478009671 cites W2066614093 @default.
- W2478009671 cites W2067849514 @default.
- W2478009671 cites W2069745890 @default.
- W2478009671 cites W2081608699 @default.
- W2478009671 cites W2082754144 @default.
- W2478009671 cites W2084225258 @default.
- W2478009671 cites W2086341481 @default.
- W2478009671 cites W2087504594 @default.
- W2478009671 cites W2091488548 @default.
- W2478009671 cites W2094844881 @default.
- W2478009671 cites W2113523368 @default.
- W2478009671 cites W2118212157 @default.
- W2478009671 cites W2124538529 @default.
- W2478009671 cites W2128049676 @default.
- W2478009671 cites W2131842322 @default.
- W2478009671 cites W2135094694 @default.
- W2478009671 cites W2137726553 @default.
- W2478009671 cites W2137900190 @default.
- W2478009671 cites W2141710896 @default.
- W2478009671 cites W2143766390 @default.
- W2478009671 cites W2172149060 @default.
- W2478009671 cites W2175956763 @default.
- W2478009671 cites W2178343701 @default.
- W2478009671 cites W2203529514 @default.
- W2478009671 cites W2203848459 @default.
- W2478009671 cites W2265737926 @default.
- W2478009671 cites W2266715901 @default.
- W2478009671 cites W2270015583 @default.
- W2478009671 cites W2284425601 @default.
- W2478009671 cites W2287054571 @default.
- W2478009671 cites W2287131993 @default.
- W2478009671 cites W2336583529 @default.
- W2478009671 cites W2337173785 @default.
- W2478009671 cites W2338909114 @default.
- W2478009671 cites W2398409235 @default.
- W2478009671 cites W2400426510 @default.
- W2478009671 cites W2404400546 @default.
- W2478009671 cites W2407807942 @default.
- W2478009671 cites W2408864648 @default.
- W2478009671 cites W2409690622 @default.
- W2478009671 cites W2414610573 @default.
- W2478009671 cites W2417195636 @default.
- W2478009671 cites W268626680 @default.
- W2478009671 doi "https://doi.org/10.1016/b978-012324751-3/50042-5" @default.
- W2478009671 hasPublicationYear "2004" @default.
- W2478009671 type Work @default.
- W2478009671 sameAs 2478009671 @default.
- W2478009671 citedByCount "0" @default.
- W2478009671 crossrefType "book-chapter" @default.
- W2478009671 hasAuthorship W2478009671A5026572261 @default.
- W2478009671 hasConcept C121332964 @default.