FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2478604675> ?p ?o ?g. }

• W2478604675 endingPage "fnw187" @default.
• W2478604675 startingPage "fnw187" @default.
• W2478604675 abstract "Actin-like MreB paralogs play important roles in cell shape maintenance, cell wall synthesis and the regulation of the D,L-endopeptidases, CwlO and LytE. The gram-positive bacteria, Bacillus amyloliquefaciens LL3, is a poly-γ-glutamic acid (γ-PGA) producing strain that contains three MreB paralogs: MreB, Mbl and MreBH. In B. amyloliquefaciens, CwlO and LytE can degrade γ-PGA. In this study, we aimed to test the hypothesis that modulating transcript levels of MreB paralogs would alter the synthesis and degradation of γ-PGA. The results showed that overexpression or inhibition of MreB, Mbl or MreBH had distinct effects on cell morphology and the molecular weight of the γ-PGA products. In fermentation medium, cells of mreB inhibition mutant were 50.2% longer than LL3, and the γ-PGA titer increased by 55.7%. However, changing the expression level of mbl showed only slight effects on the morphology, γ-PGA molecular weight and titer. In the mreBH inhibition mutant, γ-PGA production and its molecular weight increased by 56.7% and 19.4%, respectively. These results confirmed our hypothesis that suppressing the expression of MreB paralogs might reduce γ-PGA degradation, and that improving the cell size could strengthen γ-PGA synthesis. This is the first report of enhanced γ-PGA production via suppression of actin-like MreB paralogs." @default.
• W2478604675 created "2016-08-23" @default.
• W2478604675 creator A5014251275 @default.
• W2478604675 creator A5024392134 @default.
• W2478604675 creator A5029610803 @default.
• W2478604675 creator A5032953812 @default.
• W2478604675 creator A5037053656 @default.
• W2478604675 creator A5041574363 @default.
• W2478604675 creator A5073949418 @default.
• W2478604675 creator A5074962256 @default.
• W2478604675 date "2016-07-31" @default.
• W2478604675 modified "2023-10-03" @default.
• W2478604675 title "Effects of MreB paralogs on poly-γ-glutamic acid synthesis and cell morphology in<i>Bacillus amyloliquefaciens</i>" @default.
• W2478604675 cites W1802371236 @default.
• W2478604675 cites W1968425270 @default.
• W2478604675 cites W1973008729 @default.
• W2478604675 cites W1990834279 @default.
• W2478604675 cites W2004766096 @default.
• W2478604675 cites W2012524424 @default.
• W2478604675 cites W2026037710 @default.
• W2478604675 cites W2043587098 @default.
• W2478604675 cites W2044530679 @default.
• W2478604675 cites W2044804673 @default.
• W2478604675 cites W2046246082 @default.
• W2478604675 cites W2052234972 @default.
• W2478604675 cites W2055256550 @default.
• W2478604675 cites W2060004427 @default.
• W2478604675 cites W2074412364 @default.
• W2478604675 cites W2079406364 @default.
• W2478604675 cites W2083311703 @default.
• W2478604675 cites W2088631531 @default.
• W2478604675 cites W2088936250 @default.
• W2478604675 cites W2110162664 @default.
• W2478604675 cites W2119619536 @default.
• W2478604675 cites W2128000228 @default.
• W2478604675 cites W2129530757 @default.
• W2478604675 cites W2138767849 @default.
• W2478604675 cites W2152198500 @default.
• W2478604675 cites W2165629453 @default.
• W2478604675 cites W2217118616 @default.
• W2478604675 doi "https://doi.org/10.1093/femsle/fnw187" @default.
• W2478604675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27481703" @default.
• W2478604675 hasPublicationYear "2016" @default.
• W2478604675 type Work @default.
• W2478604675 sameAs 2478604675 @default.
• W2478604675 citedByCount "13" @default.
• W2478604675 countsByYear W24786046752018 @default.
• W2478604675 countsByYear W24786046752019 @default.
• W2478604675 countsByYear W24786046752020 @default.
• W2478604675 countsByYear W24786046752021 @default.
• W2478604675 countsByYear W24786046752022 @default.
• W2478604675 countsByYear W24786046752023 @default.
• W2478604675 crossrefType "journal-article" @default.
• W2478604675 hasAuthorship W2478604675A5014251275 @default.
• W2478604675 hasAuthorship W2478604675A5024392134 @default.
• W2478604675 hasAuthorship W2478604675A5029610803 @default.
• W2478604675 hasAuthorship W2478604675A5032953812 @default.
• W2478604675 hasAuthorship W2478604675A5037053656 @default.
• W2478604675 hasAuthorship W2478604675A5041574363 @default.
• W2478604675 hasAuthorship W2478604675A5073949418 @default.
• W2478604675 hasAuthorship W2478604675A5074962256 @default.
• W2478604675 hasBestOaLocation W24786046751 @default.
• W2478604675 hasConcept C100544194 @default.
• W2478604675 hasConcept C104317684 @default.
• W2478604675 hasConcept C105702510 @default.
• W2478604675 hasConcept C12554922 @default.
• W2478604675 hasConcept C125705527 @default.
• W2478604675 hasConcept C142669718 @default.
• W2478604675 hasConcept C143065580 @default.
• W2478604675 hasConcept C1491633281 @default.
• W2478604675 hasConcept C185592680 @default.
• W2478604675 hasConcept C2777811704 @default.
• W2478604675 hasConcept C2778022156 @default.
• W2478604675 hasConcept C55493867 @default.
• W2478604675 hasConcept C62551211 @default.
• W2478604675 hasConcept C86803240 @default.
• W2478604675 hasConcept C89423630 @default.
• W2478604675 hasConcept C95444343 @default.
• W2478604675 hasConceptScore W2478604675C100544194 @default.
• W2478604675 hasConceptScore W2478604675C104317684 @default.
• W2478604675 hasConceptScore W2478604675C105702510 @default.
• W2478604675 hasConceptScore W2478604675C12554922 @default.
• W2478604675 hasConceptScore W2478604675C125705527 @default.
• W2478604675 hasConceptScore W2478604675C142669718 @default.
• W2478604675 hasConceptScore W2478604675C143065580 @default.
• W2478604675 hasConceptScore W2478604675C1491633281 @default.
• W2478604675 hasConceptScore W2478604675C185592680 @default.
• W2478604675 hasConceptScore W2478604675C2777811704 @default.
• W2478604675 hasConceptScore W2478604675C2778022156 @default.
• W2478604675 hasConceptScore W2478604675C55493867 @default.
• W2478604675 hasConceptScore W2478604675C62551211 @default.
• W2478604675 hasConceptScore W2478604675C86803240 @default.
• W2478604675 hasConceptScore W2478604675C89423630 @default.
• W2478604675 hasConceptScore W2478604675C95444343 @default.
• W2478604675 hasIssue "17" @default.
• W2478604675 hasLocation W24786046751 @default.
• W2478604675 hasLocation W24786046752 @default.
• W2478604675 hasOpenAccess W2478604675 @default.

• next