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- W247888911 abstract "Publisher Summary This chapter examines the interaction between chromium and insulin. It is known that chromium deficiency results in a progressive impairment of intravenous glucose tolerance, which can be prevented and cured by adding chromium-rich foods or pure chromium complexes to the diet. Soon after this discovery, attempts to identify the mode and site of action of chromium pointed to a close interaction of this essential trace element with insulin. In one study, epididymal fat tissue, obtained from chromium-deficient rats, responded to insulin in vitro with a very small increase, but the addition of chromium compounds, ineffective by itself, significantly stimulated the tissue's response to the hormone. It has also been demonstrated that in young, healthy, presumably chromium-sufficient subjects, plasma chromium acutely increases, following a glucose load. This release of chromium into the plasma is probably mediated by the increase of plasma insulin concentrations. The increment of chromium in plasma is transient, with peaks appearing between 30 and 120 min following the glucose administration and a subsequent return to fasting values." @default.
- W247888911 created "2016-06-24" @default.
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- W247888911 date "1981-01-01" @default.
- W247888911 modified "2023-09-25" @default.
- W247888911 title "THE INTERACTION BETWEEN CHROMIUM AND INSULIN" @default.
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- W247888911 doi "https://doi.org/10.1016/b978-0-08-026825-5.50019-x" @default.
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