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- W2478892891 abstract "Transposable genetic elements were first postulated by Barbara McClintock in the late 1940s to account for unusual patterns of inheritance of pigment distribution on the cobs of maize. During the next 20 years, McClintock, working at the Cold Spring Harbor Laboratories, New York, was able to show by painstaking genetic analysis that these controlling elements could not only move from one site in the genome to another but also could suppress gene activity, cause localised mutagenicity, induce chromosome breakage at the site where they were inserted, and regulate gene activity during development. However, the concept of mobile genetic elements was so contrary to the genetic wisdom of the 1950s that most geneticists rejected the concept and failed to realise the far-reaching consequences of McClintock’s discoveries." @default.
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- W2478892891 date "1988-01-01" @default.
- W2478892891 modified "2023-09-25" @default.
- W2478892891 title "Transposable Genetic Elements" @default.
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- W2478892891 doi "https://doi.org/10.1007/978-1-349-19491-9_7" @default.
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