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• W2479004583 endingPage "818" @default.
• W2479004583 startingPage "807" @default.
• W2479004583 abstract "Publisher SummaryThis chapter discusses the clinical features, pathophysiology, genetic features, and treatment of non-bullous skin diseases—namely, alopecia, vitiligo, psoriasis, and urticaria. The pathogenesis of these diseases is multifactorial and autoimmune mechanisms are often only one component of a complex pathophysiology. Some of these diseases typically affect only the skin and do not involve other organ systems, unlike the systemic autoimmune disorders. However, subsets of patients may be identified who develop either another autoimmune disease, such as Hashimoto's thyroiditis, or in whom another organ systemis involved, such as the joints. The pathophysiologic background of these diseases notably includes an abnormal T-cell response, but also autoantibody production against self-antigens within the skin. Furthermore, treatment of these diseases includes immunosuppressive and immune-modulating agents. However, in this regard, the severity of the disease has to be considered in relation to the costs of the drug and its potential side effects." @default.
• W2479004583 created "2016-08-23" @default.
• W2479004583 creator A5000312441 @default.
• W2479004583 creator A5018780132 @default.
• W2479004583 date "2006-01-01" @default.
• W2479004583 modified "2023-10-02" @default.
• W2479004583 title "Non-Bullous Skin Diseases: Alopecia, Vitiligo Psoriasis, and Urticaria" @default.
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