Matches in SemOpenAlex for { <https://semopenalex.org/work/W2479205364> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2479205364 endingPage "13" @default.
- W2479205364 startingPage "706" @default.
- W2479205364 abstract "At the moment there are no standard guidelines for the treatment of autoimmune congenital heart block (CHB). We set out to carry out a prospective cohort study to evaluate the benefits, limits, and safety of a combined therapy protocol to treat antibody-related CHB.Twelve consecutive pregnant patients positive to anti-SSA/Ro ± anti-SSB/La antibodies in whom CHB was detected were prospectively evaluated from 2009 to 2014. The treatment protocol consisted of: weekly plasmapheresis, fortnightly intravenous immunoglobulins (IVIG), and daily 4 mg betamethasone from CHB detection until delivery; IVIG was administered to the neonates soon after birth.At the time CHB was detected, six of the foetuses presented atrioventricular blocks of 2(nd) degree type and six of 3(rd) degree type. Two of the foetuses with a 2(nd) degree block reverted to a 1st degree block and one to a normal atrioventricular conduction. The condition was stable throughout the pregnancy in the other three cases of 2(nd) degree block. All six 3(rd) degree blocks were stable during pregnancy and confirmed at birth. After a mean of 37.6 months ± 19.6 SD post-birth, the infants with 1st, normal sinus rhythm, and 2(nd) degree blocks at birth were all found to be stable. During the follow-up (29 months ± 19.8 SD), pacemakers were implanted in three of the six infants with 3(rd) degree blocks.This combined therapy seems to be effective and safe in treating 2(nd) degree CHB, while its efficacy in treating 3rd degree CHB remains to be established." @default.
- W2479205364 created "2016-08-23" @default.
- W2479205364 creator A5002713339 @default.
- W2479205364 creator A5006442136 @default.
- W2479205364 creator A5033159977 @default.
- W2479205364 creator A5051346252 @default.
- W2479205364 creator A5054501484 @default.
- W2479205364 creator A5066077173 @default.
- W2479205364 creator A5071910442 @default.
- W2479205364 creator A5085761102 @default.
- W2479205364 creator A5087432225 @default.
- W2479205364 date "2016-07-08" @default.
- W2479205364 modified "2023-10-16" @default.
- W2479205364 title "Plasmapheresis, intravenous immunoglobulins and bethametasone - a combined protocol to treat autoimmune congenital heart block: a prospective cohort study." @default.
- W2479205364 cites W2588457499 @default.
- W2479205364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27385463" @default.
- W2479205364 hasPublicationYear "2016" @default.
- W2479205364 type Work @default.
- W2479205364 sameAs 2479205364 @default.
- W2479205364 citedByCount "15" @default.
- W2479205364 countsByYear W24792053642017 @default.
- W2479205364 countsByYear W24792053642019 @default.
- W2479205364 countsByYear W24792053642020 @default.
- W2479205364 countsByYear W24792053642021 @default.
- W2479205364 countsByYear W24792053642022 @default.
- W2479205364 countsByYear W24792053642023 @default.
- W2479205364 crossrefType "journal-article" @default.
- W2479205364 hasAuthorship W2479205364A5002713339 @default.
- W2479205364 hasAuthorship W2479205364A5006442136 @default.
- W2479205364 hasAuthorship W2479205364A5033159977 @default.
- W2479205364 hasAuthorship W2479205364A5051346252 @default.
- W2479205364 hasAuthorship W2479205364A5054501484 @default.
- W2479205364 hasAuthorship W2479205364A5066077173 @default.
- W2479205364 hasAuthorship W2479205364A5071910442 @default.
- W2479205364 hasAuthorship W2479205364A5085761102 @default.
- W2479205364 hasAuthorship W2479205364A5087432225 @default.
- W2479205364 hasConcept C126322002 @default.
- W2479205364 hasConcept C141071460 @default.
- W2479205364 hasConcept C159654299 @default.
- W2479205364 hasConcept C187212893 @default.
- W2479205364 hasConcept C188816634 @default.
- W2479205364 hasConcept C203014093 @default.
- W2479205364 hasConcept C2778557577 @default.
- W2479205364 hasConcept C2778842783 @default.
- W2479205364 hasConcept C2779234561 @default.
- W2479205364 hasConcept C2781162121 @default.
- W2479205364 hasConcept C46973012 @default.
- W2479205364 hasConcept C54355233 @default.
- W2479205364 hasConcept C71924100 @default.
- W2479205364 hasConcept C72563966 @default.
- W2479205364 hasConcept C86803240 @default.
- W2479205364 hasConceptScore W2479205364C126322002 @default.
- W2479205364 hasConceptScore W2479205364C141071460 @default.
- W2479205364 hasConceptScore W2479205364C159654299 @default.
- W2479205364 hasConceptScore W2479205364C187212893 @default.
- W2479205364 hasConceptScore W2479205364C188816634 @default.
- W2479205364 hasConceptScore W2479205364C203014093 @default.
- W2479205364 hasConceptScore W2479205364C2778557577 @default.
- W2479205364 hasConceptScore W2479205364C2778842783 @default.
- W2479205364 hasConceptScore W2479205364C2779234561 @default.
- W2479205364 hasConceptScore W2479205364C2781162121 @default.
- W2479205364 hasConceptScore W2479205364C46973012 @default.
- W2479205364 hasConceptScore W2479205364C54355233 @default.
- W2479205364 hasConceptScore W2479205364C71924100 @default.
- W2479205364 hasConceptScore W2479205364C72563966 @default.
- W2479205364 hasConceptScore W2479205364C86803240 @default.
- W2479205364 hasIssue "4" @default.
- W2479205364 hasLocation W24792053641 @default.
- W2479205364 hasOpenAccess W2479205364 @default.
- W2479205364 hasPrimaryLocation W24792053641 @default.
- W2479205364 hasRelatedWork W1907365116 @default.
- W2479205364 hasRelatedWork W1985903047 @default.
- W2479205364 hasRelatedWork W1988249564 @default.
- W2479205364 hasRelatedWork W2031615899 @default.
- W2479205364 hasRelatedWork W2064341951 @default.
- W2479205364 hasRelatedWork W2416444718 @default.
- W2479205364 hasRelatedWork W2418213515 @default.
- W2479205364 hasRelatedWork W2479205364 @default.
- W2479205364 hasRelatedWork W3132496459 @default.
- W2479205364 hasRelatedWork W4236587835 @default.
- W2479205364 hasVolume "34" @default.
- W2479205364 isParatext "false" @default.
- W2479205364 isRetracted "false" @default.
- W2479205364 magId "2479205364" @default.
- W2479205364 workType "article" @default.