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• W2479405940 abstract "Anagen hair bulb apillae, interfollicular dermal fibroblasts, and interfollicular K eratinocytes isolated from fronto-parietal scalp biopsies as well as outer root sheath keratinocytes from plucked anagen hairs were separately grown in subculture for 14 d. The effect of different concentrations (2.4 nM17.3 ,uM) of testosterone, dihydrotestosterone, and the antiandrogens cyproterone acetate or 17cr-propylmesterolone on growth behavior of the mesenchymal and epithelial cell ty es of the hair follicle were comparatively studied by means o P growth curves, cell doubling times, and 3H-thymidine incorporation. For control, all cell lines were subcultured in hormone-free medium. Testosterone and dihydrotestosterone (345 nM) significantly reduced proliferation of papilla cells compared with dermal fibroblasts ( cytes compared wit R < 0.01) and outer root sheath keratinointerfollicular keratinocytes ( as well as compared with cells cultured in contra P < O.Ol)," @default.
• W2479405940 created "2016-08-23" @default.
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• W2479405940 date "1993-01-01" @default.
• W2479405940 modified "2023-09-23" @default.
• W2479405940 title "Sex Hormones and Antiandro Growth of Dermal Papilla H ens Influence In Vitro Ce Is and Outer Root Sheath Keratinocytes of Human Hair Follicles" @default.
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