Matches in SemOpenAlex for { <https://semopenalex.org/work/W2479486795> ?p ?o ?g. }
- W2479486795 endingPage "198" @default.
- W2479486795 startingPage "187" @default.
- W2479486795 abstract "Hot flashes are the most common symptom associated with menopause, although prevalence estimates are lower in some rural and non-Western areas. The symptoms are characteristic of a heat-dissipation response and consist of sweating on the face, neck, and chest, as well as peripheral vasodilation. Although hot flashes clearly accompany the estrogen withdrawal at menopause, estrogen alone is not responsible because levels do not differ between symptomatic and asymptomatic women. Recently obtained evidence, using a rapidly responding ingested telemetry pill shows that the thermoneutral zone, within which sweating, peripheral vasodilation, and shivering do not occur, is virtually nonexistent in symptomatic women but normal in asymptomatic women. Thus, small temperature elevations preceding hot flashes acting within a reduced thermoneutral zone constitute the triggering mechanism. Central sympathetic activation is elevated in symptomatic women, which, in animal studies, reduces the thermoneutral zone. Clonidine reduces central sympathetic activation, widens the thermoneutral zone, and ameliorates hot flashes. Estrogen virtually eliminates hot flashes and widens the thermoneutral zone, but the pathway through which this occurs is not known. Behavioral relaxation procedures reduce hot flash frequency to the same extent as clonidine, but their mechanism of action is also not understood." @default.
- W2479486795 created "2016-08-23" @default.
- W2479486795 creator A5073840899 @default.
- W2479486795 date "2007-01-01" @default.
- W2479486795 modified "2023-10-14" @default.
- W2479486795 title "Menopausal Hot Flashes" @default.
- W2479486795 cites W1498014128 @default.
- W2479486795 cites W1513814558 @default.
- W2479486795 cites W1532687908 @default.
- W2479486795 cites W1586699954 @default.
- W2479486795 cites W1593442063 @default.
- W2479486795 cites W172588831 @default.
- W2479486795 cites W1832376984 @default.
- W2479486795 cites W1903043018 @default.
- W2479486795 cites W1932045453 @default.
- W2479486795 cites W1963908502 @default.
- W2479486795 cites W1964407044 @default.
- W2479486795 cites W1966334621 @default.
- W2479486795 cites W1968923104 @default.
- W2479486795 cites W1970769902 @default.
- W2479486795 cites W1973757681 @default.
- W2479486795 cites W1978027412 @default.
- W2479486795 cites W1979122053 @default.
- W2479486795 cites W1979615757 @default.
- W2479486795 cites W1981435872 @default.
- W2479486795 cites W1981523260 @default.
- W2479486795 cites W1983259825 @default.
- W2479486795 cites W1983877611 @default.
- W2479486795 cites W1984214466 @default.
- W2479486795 cites W1985697512 @default.
- W2479486795 cites W1988814502 @default.
- W2479486795 cites W1993327239 @default.
- W2479486795 cites W1994994489 @default.
- W2479486795 cites W1997054444 @default.
- W2479486795 cites W1998564560 @default.
- W2479486795 cites W1999624995 @default.
- W2479486795 cites W2001625528 @default.
- W2479486795 cites W2005911905 @default.
- W2479486795 cites W2011414304 @default.
- W2479486795 cites W2011505955 @default.
- W2479486795 cites W2011892107 @default.
- W2479486795 cites W2014300456 @default.
- W2479486795 cites W2014380747 @default.
- W2479486795 cites W2015467582 @default.
- W2479486795 cites W2019549238 @default.
- W2479486795 cites W2021972583 @default.
- W2479486795 cites W2022076582 @default.
- W2479486795 cites W2024399386 @default.
- W2479486795 cites W2024733475 @default.
- W2479486795 cites W2025764883 @default.
- W2479486795 cites W2026301643 @default.
- W2479486795 cites W2027298599 @default.
- W2479486795 cites W2035300926 @default.
- W2479486795 cites W2038639749 @default.
- W2479486795 cites W2038781089 @default.
- W2479486795 cites W2038976913 @default.
- W2479486795 cites W2039204317 @default.
- W2479486795 cites W2039829070 @default.
- W2479486795 cites W2040371092 @default.
- W2479486795 cites W2041744541 @default.
- W2479486795 cites W2044267303 @default.
- W2479486795 cites W2044405011 @default.
- W2479486795 cites W2050654508 @default.
- W2479486795 cites W2051253645 @default.
- W2479486795 cites W2054466555 @default.
- W2479486795 cites W2056664311 @default.
- W2479486795 cites W2061166082 @default.
- W2479486795 cites W2063802291 @default.
- W2479486795 cites W2065988348 @default.
- W2479486795 cites W2073133700 @default.
- W2479486795 cites W2073139511 @default.
- W2479486795 cites W2076559704 @default.
- W2479486795 cites W2077254282 @default.
- W2479486795 cites W2078193003 @default.
- W2479486795 cites W2078943228 @default.
- W2479486795 cites W2079087475 @default.
- W2479486795 cites W2079590945 @default.
- W2479486795 cites W2084667980 @default.
- W2479486795 cites W2087219606 @default.
- W2479486795 cites W2091649902 @default.
- W2479486795 cites W2091700599 @default.
- W2479486795 cites W2093930904 @default.
- W2479486795 cites W2094785532 @default.
- W2479486795 cites W2106001984 @default.
- W2479486795 cites W2106887831 @default.
- W2479486795 cites W2108973772 @default.
- W2479486795 cites W2124167012 @default.
- W2479486795 cites W2133675074 @default.
- W2479486795 cites W2140191831 @default.
- W2479486795 cites W2143819464 @default.
- W2479486795 cites W2146624619 @default.
- W2479486795 cites W2149671999 @default.
- W2479486795 cites W2152316741 @default.
- W2479486795 cites W2152424231 @default.
- W2479486795 cites W2162257271 @default.
- W2479486795 cites W2166257591 @default.
- W2479486795 cites W2167000872 @default.
- W2479486795 cites W2169078759 @default.