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- W2479889622 endingPage "193" @default.
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- W2479889622 abstract "The capability of mixed polymer brush systems to modify and switch physico-chemical properties of biointerfaces is demonstrated in this paper. Mixed brushes were composed of the temperature sensitive polymer poly(N-isopropyl acrylamide) (PNIPAAM) and two polyelectrolytes, poly(2-vinylpyridine) (P2VP) and poly(acrylic acid) (PAA). Using these polymers binary brushes were prepared, the first one consisting of PNIPAAM – P2VP representing a system sensitive for temperature and pH changes, and the second one consisting of two polyelectrolytes (P2VP-PAA) showing sensitivity to pH changes of the surrounding fluid. Selected aspects concerning the environmental sensitivity as well as the protein adsorption affinity of these brushes are discussed. The stimuli-response towards temperature (PNIPAAm-P2VP) and pH (P2VP-PAA) of these binary polymer brushes was utilized to switch the adsorbed amount of protein and finally to regulate cell adhesion at brush coated surfaces." @default.
- W2479889622 created "2016-08-23" @default.
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- W2479889622 date "2012-01-01" @default.
- W2479889622 modified "2023-10-18" @default.
- W2479889622 title "Control of Protein Adsorption and Cell Adhesion by Mixed Polymer Brushes Made by the “Grafting-To” Approach" @default.
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- W2479889622 doi "https://doi.org/10.1021/bk-2012-1120.ch008" @default.
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