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- W248001836 abstract "Objective To explore the availability of microarray-based comparative analysis of gene expression profiles in transgenic and wild-type rice to evaluate the safety of unintended effects derived from transgene.Methods A rice genome oligo chip set was used and different expression genes were identified by the combination of statistic analysis and fold change threshold.The information of different expression genes was obtained by searching gene databases.Results The total of 22 different expression genes were idetified in whole rice genome,wherein the count of up-regulated genes was 13,the other were down-regulated genes.Such different expression genes were located in 11 chromosomes.Conclusion Microarray-based comparative analysis of gene expression profiles in transgenic and wild-type rice supplied no bias targets for safety evaluation of unintended effects,but microarray-based gene expression profile technology can not be broadly applied in the safety evaluation of genetically modified organisms due to the effects of natural variation and the restriction from gene function database." @default.
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- W248001836 date "2009-01-01" @default.
- W248001836 modified "2023-09-27" @default.
- W248001836 title "A microarray-based comparative analysis of gene expression profiles in transgenic and wild-type rice" @default.
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