FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2480251709> ?p ?o ?g. }

• W2480251709 endingPage "82353" @default.
• W2480251709 startingPage "82338" @default.
• W2480251709 abstract "// Qian Dong 1 , Ce Li 2 , Xiaofang Che 2 , Jinglei Qu 2 , Yibo Fan 2 , Xiaohan Li 3 , Yue Li 3 , Qian Wang 4 , Yunpeng Liu 2 , Xianghong Yang 3 , Xiujuan Qu 2 1 Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, 110004, China 2 Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China 3 Department of Pathology, Shengjing Hospital of China Medical University, Shenyang, 110004, China 4 Department of Medical Oncology, The Liaoning Provincial Tumor Hospital, Shenyang, 110042, China Correspondence to: Xianghong Yang, email: xhyang4933@vip.sina.com Xiujuan Qu, email: xiujuanqu@yahoo.com Keywords: pancreatic ductal adenocarcinoma (PDAC), microRNA-891b (miR-891b), Cbl-b, prognosis, overall survival (OS) Received: December 27, 2015      Accepted: June 01, 2016      Published: August 02, 2016 ABSTRACT Growing evidence has revealed that microRNAs could regulate the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and predict the prognosis of PDAC. Here the comparative microRNA expression profiles of the good and poor prognosis groups were performed by microRNA microarray. MicroRNA-891b (miR-891b) was screened and validated to be a prognostic predictor of PDAC in the initial group and further evaluated to be an independent predictor for the overall survival of resectable PDACs in an independent cohort. By a series of cellular and animal experiments, as well as clinical specimen analyses, miR-891b was confirmed to target the Cbl-b gene, promot the expression of tumor suppressor p21 protein and inhibit the proliferation of PDAC cells. The results provide a theoretical basis for the study of miR-891b as an independent prognostic predictor of PDAC and the role of miR-891b/Cbl-b pathway in this prediction, as well as the identification of new targets for PDAC." @default.
• W2480251709 created "2016-08-23" @default.
• W2480251709 creator A5006455181 @default.
• W2480251709 creator A5022309774 @default.
• W2480251709 creator A5027439235 @default.
• W2480251709 creator A5029512731 @default.
• W2480251709 creator A5038645053 @default.
• W2480251709 creator A5039230721 @default.
• W2480251709 creator A5044367029 @default.
• W2480251709 creator A5046225712 @default.
• W2480251709 creator A5080003280 @default.
• W2480251709 creator A5081310064 @default.
• W2480251709 creator A5088595151 @default.
• W2480251709 date "2016-08-02" @default.
• W2480251709 modified "2023-09-23" @default.
• W2480251709 title "MicroRNA-891b is an independent prognostic factor of pancreatic cancer by targeting Cbl-b to suppress the growth of pancreatic cancer cells" @default.
• W2480251709 cites W144423133 @default.
• W2480251709 cites W1513014113 @default.
• W2480251709 cites W1990324723 @default.
• W2480251709 cites W2012146504 @default.
• W2480251709 cites W2037890302 @default.
• W2480251709 cites W2040196391 @default.
• W2480251709 cites W2040399166 @default.
• W2480251709 cites W2048003573 @default.
• W2480251709 cites W2048986808 @default.
• W2480251709 cites W2050947533 @default.
• W2480251709 cites W2058924454 @default.
• W2480251709 cites W2079251691 @default.
• W2480251709 cites W2082634826 @default.
• W2480251709 cites W2088565779 @default.
• W2480251709 cites W2090136163 @default.
• W2480251709 cites W2090527870 @default.
• W2480251709 cites W2096066755 @default.
• W2480251709 cites W2098070754 @default.
• W2480251709 cites W2099581302 @default.
• W2480251709 cites W2118214154 @default.
• W2480251709 cites W2121091450 @default.
• W2480251709 cites W2130979840 @default.
• W2480251709 cites W2136280424 @default.
• W2480251709 cites W2138582833 @default.
• W2480251709 cites W2140336435 @default.
• W2480251709 cites W2145403987 @default.
• W2480251709 cites W2146729949 @default.
• W2480251709 cites W2154568166 @default.
• W2480251709 cites W2158134441 @default.
• W2480251709 cites W2162673078 @default.
• W2480251709 cites W2166653998 @default.
• W2480251709 cites W2167014039 @default.
• W2480251709 cites W2744383407 @default.
• W2480251709 cites W2917837889 @default.
• W2480251709 doi "https://doi.org/10.18632/oncotarget.11001" @default.
• W2480251709 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5347695" @default.
• W2480251709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27494897" @default.
• W2480251709 hasPublicationYear "2016" @default.
• W2480251709 type Work @default.
• W2480251709 sameAs 2480251709 @default.
• W2480251709 citedByCount "20" @default.
• W2480251709 countsByYear W24802517092017 @default.
• W2480251709 countsByYear W24802517092018 @default.
• W2480251709 countsByYear W24802517092019 @default.
• W2480251709 countsByYear W24802517092020 @default.
• W2480251709 countsByYear W24802517092021 @default.
• W2480251709 countsByYear W24802517092022 @default.
• W2480251709 countsByYear W24802517092023 @default.
• W2480251709 crossrefType "journal-article" @default.
• W2480251709 hasAuthorship W2480251709A5006455181 @default.
• W2480251709 hasAuthorship W2480251709A5022309774 @default.
• W2480251709 hasAuthorship W2480251709A5027439235 @default.
• W2480251709 hasAuthorship W2480251709A5029512731 @default.
• W2480251709 hasAuthorship W2480251709A5038645053 @default.
• W2480251709 hasAuthorship W2480251709A5039230721 @default.
• W2480251709 hasAuthorship W2480251709A5044367029 @default.
• W2480251709 hasAuthorship W2480251709A5046225712 @default.
• W2480251709 hasAuthorship W2480251709A5080003280 @default.
• W2480251709 hasAuthorship W2480251709A5081310064 @default.
• W2480251709 hasAuthorship W2480251709A5088595151 @default.
• W2480251709 hasBestOaLocation W24802517091 @default.
• W2480251709 hasConcept C104317684 @default.
• W2480251709 hasConcept C121608353 @default.
• W2480251709 hasConcept C126322002 @default.
• W2480251709 hasConcept C143998085 @default.
• W2480251709 hasConcept C145059251 @default.
• W2480251709 hasConcept C2780210213 @default.
• W2480251709 hasConcept C2781182431 @default.
• W2480251709 hasConcept C2992026798 @default.
• W2480251709 hasConcept C502942594 @default.
• W2480251709 hasConcept C55493867 @default.
• W2480251709 hasConcept C71924100 @default.
• W2480251709 hasConcept C72563966 @default.
• W2480251709 hasConcept C86803240 @default.
• W2480251709 hasConceptScore W2480251709C104317684 @default.
• W2480251709 hasConceptScore W2480251709C121608353 @default.
• W2480251709 hasConceptScore W2480251709C126322002 @default.
• W2480251709 hasConceptScore W2480251709C143998085 @default.
• W2480251709 hasConceptScore W2480251709C145059251 @default.
• W2480251709 hasConceptScore W2480251709C2780210213 @default.
• W2480251709 hasConceptScore W2480251709C2781182431 @default.
• W2480251709 hasConceptScore W2480251709C2992026798 @default.

• next