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- W2480284787 endingPage "699" @default.
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- W2480284787 abstract "Uncoupling proteins (UCPs) mediate inducible proton conductance in the mitochondrial inner membrane. Herein, we summarize our knowledge regarding UCPs in invertebrates. Since 2001, the presence of UCPs has been demonstrated in nematodes, mollusks, amphioxi, and insects. We discuss the following important issues concerning invertebrate UCPs: their evolutionary relationships, molecular and functional properties, and physiological impact. Evolutionary analysis indicates that the branch of vertebrate and invertebrate UCP4-5 diverged early in the evolutionary process prior to the divergence of the animal groups. Several proposed physiological roles of invertebrate UCPs are energy control, metabolic balance, and preventive action against oxidative stress. © 2016 IUBMB Life, 68(9):691–699, 2016" @default.
- W2480284787 created "2016-08-23" @default.
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- W2480284787 date "2016-07-07" @default.
- W2480284787 modified "2023-10-18" @default.
- W2480284787 title "Uncoupling proteins of invertebrates: A review" @default.
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- W2480284787 doi "https://doi.org/10.1002/iub.1535" @default.
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