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- W2480361488 abstract "R A L A B ST R A C T S distribution of mean hour-to-hour differences was also used to identify those with particularly labile heart rates (HR). Results: A total of 133 patients with a mean age 71+10 years, 50% male, 14% with a pacemaker and a mean hourly HR 72+14 bpm were studied. Most (89%) had persistent AF (median time in AF 39%, IQR 0, 100%). Overall, 19 of 44 patients intended for rhythm control (43%) were in AF >10% of the recording time. Of these, 14 (32%) were in AF for 100% of the time. Among a number of identified correlates, increasing thrombo-embolic risk was associated with less rhythm control (adjusted OR 0.39; 95% CI 0.23 to 0.68 per CHA2DS2-VASc score). Of 89 patients with intended rate control, 63 (71%) patients achieved a HR target of 90% of recording time with 22 patients (25%) recorded in sinus rhythm for the entire recording. Those patients in the upper quartile of mean hour-to-hour HR variability were identified as persistently labile (n1⁄433); mean HR 82+14 bpm. A further group (n1⁄422) with periodically labile HRs (17%) predominantly during the day were identified; mean HR 72+12 bpm. On an adjusted basis, those with coronary artery disease (OR 0.34; 95% CI 0.13 to 0.91) or renal disease/dysfunction (OR 0.24; 95% CI 0.06 to 0.98) were significantly less likely to demonstrate stable HR control (n1⁄478 mean HR 67+12 bpm; p<0.001 versus labile groups). Conclusion: Post-discharge ECG Holter monitoring of AF patients represents a valuable tool to identify deviations in intended rhythm/rate control and adjust therapeutic management accordingly. It may also identify particularly high risk individuals who demonstrate labile HRs and require more intensive surveillance and management to obtain clinical stability. Disclosure of Interest: None Declared" @default.
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- W2480361488 date "2012-11-15" @default.
- W2480361488 modified "2023-09-24" @default.
- W2480361488 title "The Effects of Cashew Consumption on Serum Glucose, Insulin and Lipoprotein in Type 2 Diabetic Patients" @default.
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