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- W2480498540 abstract "The identification of 5-HT receptor families and its transporter in mammalian species and drugs selective for these sites have allowed dissecting their participation in learning and memory. Importantly, some 5-HT drugs may present promnesic and/or antiamnesic effects. 5-HT consists that it has diverse pharmacological and genetic tools, neurotoxins, receptor agonist and antagonists and a well studied signaling and synaptic modulation in mammal species. Growing evidence indicates that 5-HT receptors and SERT are involved in normal, pathophysiological and therapeutic aspects of learning and memory. However, 5-HT has been linked to emotional and motivational aspects of human behavior, including anxiety, depression, impulsivity, etc; hence, whether the role of serotonin is related to memory and/or behavioral/emotional aspects, it remains an important question and evidence revised is supporting the former. Whether 5-HT markers directly or indirectly participate and/or contribute to the physiological and pharmacological basis of memory and its pathogenesis is a timely question and they seem to be important neurobiological markers. 5-HT has been also implicated in diseases with memory disorders. Future works should clarify these memory dysfunctions, including delimitations." @default.
- W2480498540 created "2016-08-23" @default.
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- W2480498540 date "2014-01-01" @default.
- W2480498540 modified "2023-09-26" @default.
- W2480498540 title "5-HT Systems and Neurobiological Markers Related to Memory Systems" @default.
- W2480498540 doi "https://doi.org/10.1016/b978-0-12-800836-2.00002-7" @default.
- W2480498540 hasPublicationYear "2014" @default.
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