FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2480583087> ?p ?o ?g. }

• W2480583087 endingPage "1581" @default.
• W2480583087 startingPage "1574" @default.
• W2480583087 abstract "Background and objectives Overestimation of GFR by urinary creatinine clearance (CrCl) at lower levels of GFR has long been attributed to enhanced creatinine secretion. However, this does not take into consideration the contribution of errors in measured GFR (and CrCl) due to short-term biologic variability or test imprecision. Design, setting, participants, & measurements We analyzed cross-sectional data among 1342 participants from the Chronic Renal Insufficiency Cohort study with baseline measurement of GFR by iothalamate clearance (iGFR) and CrCl by 24-hour urine collection. We examined the CrCl/iGFR ratio classified by categories of iGFR and also by categories of CrCl. Results Overall, mean CrCl/iGFR ratio was 1.13. CrCl/iGFR ratio was higher at lower iGFR categories. In contrast, this ratio was lower at lower CrCl levels. We hypothesize these relationships could be due to measurement error, which is bolstered by replicating these trends in a simulation and modeling exercise in which there was no variation in the ratio of CrCl/iGFR with true kidney function but taking into account the effect of measurement error in both CrCl and iGFR (of magnitudes previously described in the literature). In our simulated data, the observed CrCl/iGFR ratio was higher at lower observed iGFR levels when patients were classified by categories of observed iGFR. When the same patients were classified by categories of observed CrCl, the observed CrCl/iGFR ratio was lower at lower observed CrCl levels. Conclusions The combined empirical and modeling results suggest that measurement errors (in both CrCl and iGFR) should be considered as an alternative explanation for the longstanding observation that the ratio of CrCl to iGFR gets larger as iGFR decreases." @default.
• W2480583087 created "2016-08-23" @default.
• W2480583087 creator A5001211507 @default.
• W2480583087 creator A5009449264 @default.
• W2480583087 creator A5014622979 @default.
• W2480583087 creator A5026846209 @default.
• W2480583087 creator A5059512015 @default.
• W2480583087 creator A5067724530 @default.
• W2480583087 creator A5068692636 @default.
• W2480583087 creator A5085683611 @default.
• W2480583087 date "2016-08-03" @default.
• W2480583087 modified "2023-09-27" @default.
• W2480583087 title "Measurement Error as Alternative Explanation for the Observation that CrCl/GFR Ratio is Higher at Lower GFR" @default.
• W2480583087 cites W1969488735 @default.
• W2480583087 cites W1975691702 @default.
• W2480583087 cites W1978694850 @default.
• W2480583087 cites W1980848748 @default.
• W2480583087 cites W1982634744 @default.
• W2480583087 cites W1989632116 @default.
• W2480583087 cites W1989993094 @default.
• W2480583087 cites W2004693666 @default.
• W2480583087 cites W2036789134 @default.
• W2480583087 cites W2042206096 @default.
• W2480583087 cites W2042838736 @default.
• W2480583087 cites W2046962038 @default.
• W2480583087 cites W2047944613 @default.
• W2480583087 cites W2048051429 @default.
• W2480583087 cites W2049020791 @default.
• W2480583087 cites W2050789305 @default.
• W2480583087 cites W2053601215 @default.
• W2480583087 cites W2056503496 @default.
• W2480583087 cites W2070834922 @default.
• W2480583087 cites W2072550989 @default.
• W2480583087 cites W2077856938 @default.
• W2480583087 cites W2086702076 @default.
• W2480583087 cites W2092639422 @default.
• W2480583087 cites W2102006967 @default.
• W2480583087 cites W2128168657 @default.
• W2480583087 cites W2131779076 @default.
• W2480583087 cites W2138117703 @default.
• W2480583087 cites W2141348928 @default.
• W2480583087 cites W2146105386 @default.
• W2480583087 cites W2146901169 @default.
• W2480583087 cites W2148983669 @default.
• W2480583087 cites W2160134719 @default.
• W2480583087 cites W2161465647 @default.
• W2480583087 cites W2166090859 @default.
• W2480583087 cites W2180745593 @default.
• W2480583087 doi "https://doi.org/10.2215/cjn.12821215" @default.
• W2480583087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5012489" @default.
• W2480583087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27489301" @default.
• W2480583087 hasPublicationYear "2016" @default.
• W2480583087 type Work @default.
• W2480583087 sameAs 2480583087 @default.
• W2480583087 citedByCount "10" @default.
• W2480583087 countsByYear W24805830872016 @default.
• W2480583087 countsByYear W24805830872017 @default.
• W2480583087 countsByYear W24805830872018 @default.
• W2480583087 countsByYear W24805830872020 @default.
• W2480583087 countsByYear W24805830872022 @default.
• W2480583087 countsByYear W24805830872023 @default.
• W2480583087 crossrefType "journal-article" @default.
• W2480583087 hasAuthorship W2480583087A5001211507 @default.
• W2480583087 hasAuthorship W2480583087A5009449264 @default.
• W2480583087 hasAuthorship W2480583087A5014622979 @default.
• W2480583087 hasAuthorship W2480583087A5026846209 @default.
• W2480583087 hasAuthorship W2480583087A5059512015 @default.
• W2480583087 hasAuthorship W2480583087A5067724530 @default.
• W2480583087 hasAuthorship W2480583087A5068692636 @default.
• W2480583087 hasAuthorship W2480583087A5085683611 @default.
• W2480583087 hasBestOaLocation W24805830871 @default.
• W2480583087 hasConcept C126322002 @default.
• W2480583087 hasConcept C126894567 @default.
• W2480583087 hasConcept C144174609 @default.
• W2480583087 hasConcept C159641895 @default.
• W2480583087 hasConcept C170493617 @default.
• W2480583087 hasConcept C2775960820 @default.
• W2480583087 hasConcept C2780306776 @default.
• W2480583087 hasConcept C71924100 @default.
• W2480583087 hasConceptScore W2480583087C126322002 @default.
• W2480583087 hasConceptScore W2480583087C126894567 @default.
• W2480583087 hasConceptScore W2480583087C144174609 @default.
• W2480583087 hasConceptScore W2480583087C159641895 @default.
• W2480583087 hasConceptScore W2480583087C170493617 @default.
• W2480583087 hasConceptScore W2480583087C2775960820 @default.
• W2480583087 hasConceptScore W2480583087C2780306776 @default.
• W2480583087 hasConceptScore W2480583087C71924100 @default.
• W2480583087 hasIssue "9" @default.
• W2480583087 hasLocation W24805830871 @default.
• W2480583087 hasLocation W24805830872 @default.
• W2480583087 hasLocation W24805830873 @default.
• W2480583087 hasLocation W24805830874 @default.
• W2480583087 hasOpenAccess W2480583087 @default.
• W2480583087 hasPrimaryLocation W24805830871 @default.
• W2480583087 hasRelatedWork W1544023406 @default.
• W2480583087 hasRelatedWork W1830795151 @default.
• W2480583087 hasRelatedWork W1973741567 @default.
• W2480583087 hasRelatedWork W1974378936 @default.

• next