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- W2481455061 endingPage "9056" @default.
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- W2481455061 abstract "Significance Tuberculosis is an ancient human disease that continues to affect millions of people worldwide. A crucial component of the origins of the tuberculosis bacterium remains a mystery: What were the conditions that precipitated its emergence as an obligate transmissible human pathogen? Here, we identify a connection between the emergence of tuberculosis and another major event in human prehistory, namely the discovery of controlled fire use. Our results have serious and cautionary implications for the emergence of new infectious diseases—feedback between cultural innovation and alteration of living conditions can catalyze unexpected changes with potentially devastating consequences lasting thousands of years." @default.
- W2481455061 created "2016-08-23" @default.
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- W2481455061 date "2016-07-25" @default.
- W2481455061 modified "2023-10-17" @default.
- W2481455061 title "Controlled fire use in early humans might have triggered the evolutionary emergence of tuberculosis" @default.
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- W2481455061 doi "https://doi.org/10.1073/pnas.1603224113" @default.
- W2481455061 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4987778" @default.
- W2481455061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27457933" @default.
- W2481455061 hasPublicationYear "2016" @default.
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