Matches in SemOpenAlex for { <https://semopenalex.org/work/W2481907994> ?p ?o ?g. }
- W2481907994 abstract "The mammalian central nervous system cannot regenerate axons after trauma, so remyelination following axon regeneration is rarely studied in mammals. However, as a teleost that has a strong intrinsic ability to regenerate, zebrafish can regrow axons to their original target and be rewrapped by oligodendrocytes. It is noteworthy that remyelination is as important as axon regeneration to functional recovery in neural regeneration. In this chapter, we first introduce the characteristics of the zebrafish and its unique properties for studying neural regeneration. Second, as an example, the time course of optic nerve axon regeneration and factors involved is illustrated. Third, mutants and transgenic lines for neural regeneration and remyelination studies are introduced. Fourth, in vivo imaging of neural regeneration and remyelination in zebrafish is highlighted. Last, behavior tests for evaluating functional recovery after optic nerve injury are described. To completely understand the progress of myelination and functional recovery in zebrafish, more elegant experiments that combine multiple technologies and observe multitype cell interactions should be performed in the near future." @default.
- W2481907994 created "2016-08-23" @default.
- W2481907994 creator A5013649218 @default.
- W2481907994 creator A5019246084 @default.
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- W2481907994 creator A5072707530 @default.
- W2481907994 creator A5074641183 @default.
- W2481907994 creator A5083547946 @default.
- W2481907994 date "2015-01-01" @default.
- W2481907994 modified "2023-10-16" @default.
- W2481907994 title "Functional Regeneration and Remyelination in the Zebrafish Optic Nerve" @default.
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