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- W2482783198 abstract "Cystatins refer to proteinaceous cysteine proteinase inhibitors. The oryzacystatin we found in rice is known to be the first well-defined cystatin of plant origin. Recently, we elucidated similar cystatins from corn and wheat by molecular cloning and expression studies. These small proteins contain approximately 100 amino acid residues. Each has a central Gln-Val-Val-Ala-Gly or related region which may be involved in binding with cysteine proteinases such as papain. Wheat cystatin, as well as oryzacystatin, is also characterized by having an inhibitory effect on human viruses, e.g., poliovirus, and crop insects, e.g., adzuki bean weevil which has a cysteine proteinase in its digestive tract. Our finding of such defensive functions of cereal cystatins prompted us to regenerate transgenic rice in which cystatin genes had been introduced. The expression of the introduced genes has already been confirmed. The possible utility of these new rice cultivars will be discussed." @default.
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- W2482783198 date "1995-10-05" @default.
- W2482783198 modified "2023-09-30" @default.
- W2482783198 title "Molecular Cloning of Cereal Cystatins and Evaluation of Their Antiviral and Antipest Effects" @default.
- W2482783198 doi "https://doi.org/10.1021/bk-1995-0605.ch011" @default.
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