Matches in SemOpenAlex for { <https://semopenalex.org/work/W2483556725> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2483556725 endingPage "51" @default.
- W2483556725 startingPage "41" @default.
- W2483556725 abstract "Underlying injures produced by Hemolytic Uremic Syndrome, a clinical entity defined by the triad, inclu-de: non-immune hemolytic anemia, thrombocytopenia, and organ involvement which are measured by the Trombotic Systemic Microangiopathy (TSM) process. The atypical HUS (HUSa) is a subtype of HUS in which the phenomena of TSM are the result of the lack of regulation in alternative pathway of complements on cell surfaces, secondary to a genetic cause. The key role played by the deregulation of the complement system on the damaged endothelial layer in patients with HUSa has been established; this system measures by multiple mutations and polymorphisms in the genes that encode certain regulatory proteins of the add-in has been established. Taking into account the great complement activity of physiological way during ges-tation, each day more cases of HUSa related to pregnancy, are described. There is a monoclonal antibody, Eculizumab, which inhibits the terminal complement fraction (C5). Eculizumab blocks the formation of the attack complex of the membrane, with significant long-term improvement in morbidity and mortality asso-ciated with this disease, promoting long-term recovery of renal function and with a significant reduction in the need for dialysis or plasma therapy.A case of 17 year in puerperium, who developed icteric syndrome considered as HELLP syndrome, whose atypical evolution made us think about alternative diagnosis of thrombotic microangiopathy in pregnant woman HUSa type. Discard diagnosis between sepsis, HELLP syndrome and disseminated intravascular coagulation was made. ADAMST13 measurement was taken, whose standard value allowed us to make the differential diagnosis with a Thrombotic Thrombocytopenic Purpura (TTP). In this way, we were able to achieve the clinical diagnosis of HUSa and begin treatment." @default.
- W2483556725 created "2016-08-23" @default.
- W2483556725 creator A5002276554 @default.
- W2483556725 creator A5016412678 @default.
- W2483556725 creator A5059751772 @default.
- W2483556725 date "2016-01-01" @default.
- W2483556725 modified "2023-09-25" @default.
- W2483556725 title "Thrombotic microangiophatic in the ICU, hemolytic uremic syndrome relate to pregnancy: case report and literature review" @default.
- W2483556725 doi "https://doi.org/10.22265/acnef.3.1.239" @default.
- W2483556725 hasPublicationYear "2016" @default.
- W2483556725 type Work @default.
- W2483556725 sameAs 2483556725 @default.
- W2483556725 citedByCount "0" @default.
- W2483556725 crossrefType "journal-article" @default.
- W2483556725 hasAuthorship W2483556725A5002276554 @default.
- W2483556725 hasAuthorship W2483556725A5016412678 @default.
- W2483556725 hasAuthorship W2483556725A5059751772 @default.
- W2483556725 hasBestOaLocation W24835567251 @default.
- W2483556725 hasConcept C111684460 @default.
- W2483556725 hasConcept C159654299 @default.
- W2483556725 hasConcept C177713679 @default.
- W2483556725 hasConcept C203014093 @default.
- W2483556725 hasConcept C2777637130 @default.
- W2483556725 hasConcept C2779234561 @default.
- W2483556725 hasConcept C54355233 @default.
- W2483556725 hasConcept C71924100 @default.
- W2483556725 hasConcept C86803240 @default.
- W2483556725 hasConceptScore W2483556725C111684460 @default.
- W2483556725 hasConceptScore W2483556725C159654299 @default.
- W2483556725 hasConceptScore W2483556725C177713679 @default.
- W2483556725 hasConceptScore W2483556725C203014093 @default.
- W2483556725 hasConceptScore W2483556725C2777637130 @default.
- W2483556725 hasConceptScore W2483556725C2779234561 @default.
- W2483556725 hasConceptScore W2483556725C54355233 @default.
- W2483556725 hasConceptScore W2483556725C71924100 @default.
- W2483556725 hasConceptScore W2483556725C86803240 @default.
- W2483556725 hasIssue "1" @default.
- W2483556725 hasLocation W24835567251 @default.
- W2483556725 hasOpenAccess W2483556725 @default.
- W2483556725 hasPrimaryLocation W24835567251 @default.
- W2483556725 hasRelatedWork W2363400180 @default.
- W2483556725 hasRelatedWork W2563850675 @default.
- W2483556725 hasRelatedWork W2587527433 @default.
- W2483556725 hasRelatedWork W2909878616 @default.
- W2483556725 hasRelatedWork W2972014178 @default.
- W2483556725 hasRelatedWork W2978371575 @default.
- W2483556725 hasRelatedWork W2997658095 @default.
- W2483556725 hasRelatedWork W3034705619 @default.
- W2483556725 hasRelatedWork W3196353093 @default.
- W2483556725 hasRelatedWork W4252371801 @default.
- W2483556725 hasVolume "3" @default.
- W2483556725 isParatext "false" @default.
- W2483556725 isRetracted "false" @default.
- W2483556725 magId "2483556725" @default.
- W2483556725 workType "article" @default.