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- W2483670688 abstract "This chapter discusses the sensitization of magnetic resonance (MR) signal intensity to molecular diffusion due to the application of a pair of dephasing and rephasing gradients. The movement of molecules between the two gradient pulses leads to imperfect rephasing and signal loss. The chapter reviews the parameters that affect the signal attenuation (S/S0)—where S0 is the signal intensity without gradients and S is the signal with a pair of gradients. The longer the interval between the two pulses, the greater is the chance for the water molecules to move around, which leads to more signal loss. The higher the diffusion constant (D) the greater is the chance for the water molecules to change their positions within a fixed amount of time (Δ). Another parameter is the amount of initial dephasing, which is decided by the area of the gradients. There are four parameters that dictate the amount of signal loss and among them G, Δ, and δ are experimental parameters. By changing them, the amount of signal loss (“diffusion weighting”) can be controlled, and the pair of gradients is called “diffusion-weighting gradients.”" @default.
- W2483670688 created "2016-08-23" @default.
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- W2483670688 date "2007-01-01" @default.
- W2483670688 modified "2023-09-27" @default.
- W2483670688 title "Anatomy of diffusion measurement" @default.
- W2483670688 doi "https://doi.org/10.1016/b978-044452828-5/50016-8" @default.
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