Matches in SemOpenAlex for { <https://semopenalex.org/work/W2484635162> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2484635162 abstract "Earlier in the works dedicated to the study of the relationship «structure-activity» derivatives 1H-pyrimidine4-one was found expressed anti-infl ammatory activity. Therefore, we continued to search of new NSAID among these compounds. Spectrum of pharmacological properties of 2-venylenesubstituted derivatives of 1H-pyrimidin-4one was carried out using the program PASS (Prediction of Activity Spectra for Substances). Further, for the most perspective structures was carried virtual docking on the enzyme COX-2. Detected by the results of prediction compounds-leaders were synthesized for the further pharmacological research. The dependence between the charges on carbon atome of aldehyde groups at the starting aldehydes and the yield was determined." @default.
- W2484635162 created "2016-08-23" @default.
- W2484635162 creator A5010775766 @default.
- W2484635162 date "2015-01-01" @default.
- W2484635162 modified "2023-09-24" @default.
- W2484635162 title "MOLECULAR MODELING AND SYNTHESIS OF NEW NSAIDS IN THE SERIES OF 1H-PYRIMIDIN-4-ONE DERIVATIVES" @default.
- W2484635162 hasPublicationYear "2015" @default.
- W2484635162 type Work @default.
- W2484635162 sameAs 2484635162 @default.
- W2484635162 citedByCount "0" @default.
- W2484635162 crossrefType "journal-article" @default.
- W2484635162 hasAuthorship W2484635162A5010775766 @default.
- W2484635162 hasConcept C159110408 @default.
- W2484635162 hasConcept C161790260 @default.
- W2484635162 hasConcept C178790620 @default.
- W2484635162 hasConcept C181199279 @default.
- W2484635162 hasConcept C185592680 @default.
- W2484635162 hasConcept C193042331 @default.
- W2484635162 hasConcept C202751555 @default.
- W2484635162 hasConcept C21951064 @default.
- W2484635162 hasConcept C2779825165 @default.
- W2484635162 hasConcept C41685203 @default.
- W2484635162 hasConcept C55493867 @default.
- W2484635162 hasConcept C71240020 @default.
- W2484635162 hasConcept C71924100 @default.
- W2484635162 hasConceptScore W2484635162C159110408 @default.
- W2484635162 hasConceptScore W2484635162C161790260 @default.
- W2484635162 hasConceptScore W2484635162C178790620 @default.
- W2484635162 hasConceptScore W2484635162C181199279 @default.
- W2484635162 hasConceptScore W2484635162C185592680 @default.
- W2484635162 hasConceptScore W2484635162C193042331 @default.
- W2484635162 hasConceptScore W2484635162C202751555 @default.
- W2484635162 hasConceptScore W2484635162C21951064 @default.
- W2484635162 hasConceptScore W2484635162C2779825165 @default.
- W2484635162 hasConceptScore W2484635162C41685203 @default.
- W2484635162 hasConceptScore W2484635162C55493867 @default.
- W2484635162 hasConceptScore W2484635162C71240020 @default.
- W2484635162 hasConceptScore W2484635162C71924100 @default.
- W2484635162 hasLocation W24846351621 @default.
- W2484635162 hasOpenAccess W2484635162 @default.
- W2484635162 hasPrimaryLocation W24846351621 @default.
- W2484635162 hasRelatedWork W1976863181 @default.
- W2484635162 hasRelatedWork W1998630276 @default.
- W2484635162 hasRelatedWork W2002911498 @default.
- W2484635162 hasRelatedWork W2109266878 @default.
- W2484635162 hasRelatedWork W2902103025 @default.
- W2484635162 hasRelatedWork W2911560369 @default.
- W2484635162 hasRelatedWork W2923765758 @default.
- W2484635162 hasRelatedWork W2947176388 @default.
- W2484635162 hasRelatedWork W2950200327 @default.
- W2484635162 hasRelatedWork W2950843918 @default.
- W2484635162 hasRelatedWork W3013061420 @default.
- W2484635162 hasRelatedWork W3085140437 @default.
- W2484635162 hasRelatedWork W3101672682 @default.
- W2484635162 hasRelatedWork W3136713284 @default.
- W2484635162 hasRelatedWork W3175234153 @default.
- W2484635162 hasRelatedWork W3184626387 @default.
- W2484635162 hasRelatedWork W3186215936 @default.
- W2484635162 hasRelatedWork W3204978684 @default.
- W2484635162 hasRelatedWork W3209596210 @default.
- W2484635162 hasRelatedWork W2555258604 @default.
- W2484635162 isParatext "false" @default.
- W2484635162 isRetracted "false" @default.
- W2484635162 magId "2484635162" @default.
- W2484635162 workType "article" @default.