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- W2485093417 abstract "Proving the clinical efficacy of Neisseria meningitidis serogroup B (MenB) vaccines has been difficult. There is substantial genetic (and corresponding antigenic) diversity, and serogroup B meningococcal disease is both uncommon and in decline in countries where the burden is well understood. The incidence of meningococcal disease in the United States is at a historic low (0.18 per 100,000 person-years in 2013, including serotypes A, C, W, Y, and B). However, from 2009 through 2015 there were seven outbreaks of MenB meningitis at U.S. universities that resulted in 43 cases and 3 deaths.1 Because no MenB vaccine had been approved by . . ." @default.
- W2485093417 created "2016-08-23" @default.
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- W2485093417 date "2016-07-21" @default.
- W2485093417 modified "2023-09-24" @default.
- W2485093417 title "A Challenge in Vaccine Development —Neisseria meningitidisSerogroup B" @default.
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- W2485093417 doi "https://doi.org/10.1056/nejme1606015" @default.
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