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- W2485498445 abstract "The identification and functional characterisation of von Willebrand disease (VWD) is challenging due to clinical uncertainty and limitations in test processes and panels used by laboratories, and because the classification scheme does not always permit unequivocal assignment of subtype. This article reviews contemporary alternatives to classic diagnostic approaches, including the incorporation of extended core test panels inclusive of the collagen-binding assay and the potential for desmopressin (DDAVP) challenge not only to provide therapeutic information but also to assist the better characterisation of individuals with defects or deficiencies in von Willebrand factor (VWF). Supplementary assays such as the PFA-100® and the VWF propeptide assay following DDAVP challenge are also worth considering." @default.
- W2485498445 created "2016-08-23" @default.
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- W2485498445 date "2009-01-01" @default.
- W2485498445 modified "2023-09-24" @default.
- W2485498445 title "Identification and Functional Characterisation of von Willebrand Disease" @default.
- W2485498445 doi "https://doi.org/10.17925/eoh.2009.03.1.25" @default.
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