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• W2485992248 abstract "Objective . To investigate the risk factors, clinical characteristics, treatment modalities, and outcomes in Saudi patients with HCC and propose points for early detection of the disease. Methods . Patients were stratified according to underlying risk factors for the development of HCC. Barcelona Clinic Liver Cancer (BCLC) was used for cancer staging. Treatment was classified into surgical resection/liver transplantation; locoregional ablation therapy; transarterial embolization; systemic chemotherapy; and best supportive care. Results . A total of 235 patients were included. Males had higher tumor size and incidence of portal vein thrombosis. Viral hepatitis was a risk factor in 75.7%. The most common BCLC stages were B (34.5%) and A (33.6%), and the most common radiological presentation was a single nodule of less than 5 cm. Metastases were present in 13.2%. Overall, 77 patients (32.8%) underwent a potentially curative treatment as the initial therapy. The most commonly utilized treatment modality was chemoembolization with 113 sessions in 71 patients. The overall median survival was<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mn fontstyle=italic>15.97</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle=italic>27.18</mml:mn></mml:math>months. Conclusion . HCC in Saudi Arabia is associated with high prevalence of HCV. Potentially curative therapies were underutilized in our patients. Cancer stage BCLC-B was the most frequent (34.5%) followed by BCLC-A (33.6%). The overall median survival was shorter than other studies." @default.
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• W2485992248 date "2016-01-01" @default.
• W2485992248 modified "2023-10-16" @default.
• W2485992248 title "Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience" @default.
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• W2485992248 doi "https://doi.org/10.1155/2016/1989045" @default.
• W2485992248 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4976192" @default.
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