Matches in SemOpenAlex for { <https://semopenalex.org/work/W2486104903> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2486104903 endingPage "7" @default.
- W2486104903 startingPage "53" @default.
- W2486104903 abstract "The alpha interferon treatment criteria have not been established in children with chronic hepatitis B. We report the results of a prospective study.Between 1988-1992 14 children (2 girls and 12 boys) with chronic hepatitis B received 3 million U/m2 of interferon alpha three times a week for 6 months. All patients underwent a liver biopsy that showed a pattern of chronic active hepatitis. One patient had cirrhosis. Hepatitis B surface antigen, hepatitis Be antigen and hepatitis B virus DNA had been positive in the serum in all for at least 6 months and anti-delta antibodies were negative in all. Pretreatment aminotransferase levels were at least 1.5 times the upper limit of normal.After treatment patients were followed up for at least one year (mean: 21.5 +/- 8.3 months). At the end of treatment HBV DNA was negative in 13 out of 14 patients and reappeared in one; HBeAg seroconversion was observed in 11 patients with the appearance of anti-HBe antibodies. Six patients lost the HBs antigen within 1 to 14 months after treatment. Anti-HBs antibodies did not appear in any patients and aminotransferase level normalized in 13 patients. Thirteen patients underwent liver biopsy after treatment which showed improvement in 12.Treatment with alpha interferon at doses of 3 MU/m2 is effective in children with active hepatitis B. Long-term follow up is needed to evaluate the effectiveness of this therapy." @default.
- W2486104903 created "2016-08-23" @default.
- W2486104903 creator A5002067454 @default.
- W2486104903 creator A5010945167 @default.
- W2486104903 creator A5017828971 @default.
- W2486104903 creator A5042990192 @default.
- W2486104903 creator A5054620156 @default.
- W2486104903 creator A5090680544 @default.
- W2486104903 date "1995-01-01" @default.
- W2486104903 modified "2023-10-03" @default.
- W2486104903 title "[Treatment of chronic viral hepatitis B in children with moderate doses of alpha interferon]." @default.
- W2486104903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7720991" @default.
- W2486104903 hasPublicationYear "1995" @default.
- W2486104903 type Work @default.
- W2486104903 sameAs 2486104903 @default.
- W2486104903 citedByCount "3" @default.
- W2486104903 crossrefType "journal-article" @default.
- W2486104903 hasAuthorship W2486104903A5002067454 @default.
- W2486104903 hasAuthorship W2486104903A5010945167 @default.
- W2486104903 hasAuthorship W2486104903A5017828971 @default.
- W2486104903 hasAuthorship W2486104903A5042990192 @default.
- W2486104903 hasAuthorship W2486104903A5054620156 @default.
- W2486104903 hasAuthorship W2486104903A5090680544 @default.
- W2486104903 hasConcept C126322002 @default.
- W2486104903 hasConcept C159654299 @default.
- W2486104903 hasConcept C203014093 @default.
- W2486104903 hasConcept C2522874641 @default.
- W2486104903 hasConcept C2775934546 @default.
- W2486104903 hasConcept C2775940106 @default.
- W2486104903 hasConcept C2776029263 @default.
- W2486104903 hasConcept C2776178377 @default.
- W2486104903 hasConcept C2777214474 @default.
- W2486104903 hasConcept C2777382497 @default.
- W2486104903 hasConcept C2777410769 @default.
- W2486104903 hasConcept C2777451964 @default.
- W2486104903 hasConcept C2777766500 @default.
- W2486104903 hasConcept C2780593183 @default.
- W2486104903 hasConcept C2780727368 @default.
- W2486104903 hasConcept C2781228144 @default.
- W2486104903 hasConcept C2909179924 @default.
- W2486104903 hasConcept C71924100 @default.
- W2486104903 hasConcept C90924648 @default.
- W2486104903 hasConceptScore W2486104903C126322002 @default.
- W2486104903 hasConceptScore W2486104903C159654299 @default.
- W2486104903 hasConceptScore W2486104903C203014093 @default.
- W2486104903 hasConceptScore W2486104903C2522874641 @default.
- W2486104903 hasConceptScore W2486104903C2775934546 @default.
- W2486104903 hasConceptScore W2486104903C2775940106 @default.
- W2486104903 hasConceptScore W2486104903C2776029263 @default.
- W2486104903 hasConceptScore W2486104903C2776178377 @default.
- W2486104903 hasConceptScore W2486104903C2777214474 @default.
- W2486104903 hasConceptScore W2486104903C2777382497 @default.
- W2486104903 hasConceptScore W2486104903C2777410769 @default.
- W2486104903 hasConceptScore W2486104903C2777451964 @default.
- W2486104903 hasConceptScore W2486104903C2777766500 @default.
- W2486104903 hasConceptScore W2486104903C2780593183 @default.
- W2486104903 hasConceptScore W2486104903C2780727368 @default.
- W2486104903 hasConceptScore W2486104903C2781228144 @default.
- W2486104903 hasConceptScore W2486104903C2909179924 @default.
- W2486104903 hasConceptScore W2486104903C71924100 @default.
- W2486104903 hasConceptScore W2486104903C90924648 @default.
- W2486104903 hasIssue "1" @default.
- W2486104903 hasLocation W24861049031 @default.
- W2486104903 hasOpenAccess W2486104903 @default.
- W2486104903 hasPrimaryLocation W24861049031 @default.
- W2486104903 hasRelatedWork W1965000508 @default.
- W2486104903 hasRelatedWork W1967148352 @default.
- W2486104903 hasRelatedWork W1995929908 @default.
- W2486104903 hasRelatedWork W2102245402 @default.
- W2486104903 hasRelatedWork W2157468742 @default.
- W2486104903 hasRelatedWork W2160796569 @default.
- W2486104903 hasRelatedWork W2306414401 @default.
- W2486104903 hasRelatedWork W2437946921 @default.
- W2486104903 hasRelatedWork W2444507145 @default.
- W2486104903 hasRelatedWork W3133657847 @default.
- W2486104903 hasVolume "19" @default.
- W2486104903 isParatext "false" @default.
- W2486104903 isRetracted "false" @default.
- W2486104903 magId "2486104903" @default.
- W2486104903 workType "article" @default.