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- W2486104978 abstract "This chapter discusses the pathophysiology and diagnostic approach to obstructive uropathy in the elderly. Normal urine production and flow depend on (1) hydrostatic pressure that progressively decreases from the kidney to the bladder and (2) ureteral peristalsis. Obstruction to urine flow anywhere in the system causes an increase in pressure and volume of urine proximal to the obstruction. Significant obstruction impairs renal function and if the obstruction is severe enough, the kidney may be destroyed. The symptoms and signs of urinary tract obstruction are often nonspecific, and the clinical manifestations may be dominated by the degree of renal functional impairment, by the presence of urinary tract infection, and sometimes by the extra renal signs and symptoms of the underlying pathological process, for example, local and distant metastases from tumors producing obstruction of the urinary tract. Some clinical features of urinary tract obstruction, when present, however, are sufficiently distinctive to suggest the proper diagnosis. The clinical manifestations of urinary tract obstruction can be conditioned by the duration, location, and degree of obstruction. The approach to a patient with urinary tract obstruction will depend on the clinical setting and presenting symptoms, the spectrum of which extends from the patients presenting with the acute onset of pain to the patients with acute renal failure and anuria." @default.
- W2486104978 created "2016-08-23" @default.
- W2486104978 creator A5009225253 @default.
- W2486104978 date "1987-01-01" @default.
- W2486104978 modified "2023-09-26" @default.
- W2486104978 title "Obstructive uropathy in the elderly" @default.
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