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- W248623548 abstract "Summary: The interpretation of anti-neutrophil cytoplasmic antibodies is often not an easy task and it requires profound knowledge about the discrepancy of the detection methods with consequent false positive and false negative results. In the last years, there are many attempts for a standardization of those methods in order to allow them to play a role not only as an useful serological assay but also as diagnostic criteria in the classification of ANCA associated vasculitis (AAV). The clinical interpretation of the results is complicated also because of the fact that ANCA are a heterogenous group and some of the types can be found in different chronic-inflammatory and autoimmune diseases, after the use of some drugs, and in infectious and malignant processes. That is why in this review we discuss the current immunological characteristics of the above-mentioned states and present the new understanding and trends about the diagnostic significance which ANCAs contribute to clinical practice." @default.
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- W248623548 date "2011-01-01" @default.
- W248623548 modified "2023-09-23" @default.
- W248623548 title "Diagnostic value of anti-neutrophil cytoplasmic antibodies." @default.
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