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- W2486356170 abstract "Dentofacial deformities are dys-morpho-functional disorders involving the temporomandibular joints (TMJ). Many authors have reported a TMJ improvement in dysfunctional subjects with malocclusion after orthodontic or combined orthodontic and surgical treatment particularly for the relief of pain. In particular, few studies have highlighted the demographic and clinical predictors of response to surgical treatment. To date, no genetic factor has yet been identified as a predictor of response to surgical treatment. The aim of this cohort study is therefore to identify single-nucleotide polymorphisms associated with postoperative temporomandibular disorders (TMD) or with TMJ symptoms after orthognathic surgery. Here, we found the AA genotype of SNP rs1643821 (ESR1 gene) as a risk factor for dysfunctional worsening after orthognathic surgery. In addition, we have identified TT genotype of SNP rs858339 (ENPP1 gene) as a protective factor against TMD in a population of patients with dentofacial deformities. Conversely, the heterozygous genotype AT was identified as a risk factor of TMD with respect to the rest of our population. All these elements are particularly important to bring new screening strategies and tailor future treatment. This study allows us to identify sub-populations at high risk of developing postoperative temporomandibular disorders after orthognathic surgery procedures. Many other genes of interest could be potential factors influencing the dysfunctional response to orthognathic surgery, particularly genes of the Opera cohort." @default.
- W2486356170 created "2016-08-23" @default.
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- W2486356170 date "2016-09-01" @default.
- W2486356170 modified "2023-10-02" @default.
- W2486356170 title "ENPP1 and ESR1 genotypes influence temporomandibular disorders development and surgical treatment response in dentofacial deformities" @default.
- W2486356170 cites W1502955608 @default.
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- W2486356170 cites W1572473303 @default.
- W2486356170 cites W188947268 @default.
- W2486356170 cites W1898306897 @default.
- W2486356170 cites W1916162395 @default.
- W2486356170 cites W1972154357 @default.
- W2486356170 cites W1978466333 @default.
- W2486356170 cites W1991009437 @default.
- W2486356170 cites W1991608470 @default.
- W2486356170 cites W1993136139 @default.
- W2486356170 cites W1998012046 @default.
- W2486356170 cites W1998322768 @default.
- W2486356170 cites W2000745454 @default.
- W2486356170 cites W2003723406 @default.
- W2486356170 cites W2003835853 @default.
- W2486356170 cites W2004934852 @default.
- W2486356170 cites W2010125977 @default.
- W2486356170 cites W2011545725 @default.
- W2486356170 cites W2013016273 @default.
- W2486356170 cites W2017720269 @default.
- W2486356170 cites W2019044621 @default.
- W2486356170 cites W2023571320 @default.
- W2486356170 cites W2023731184 @default.
- W2486356170 cites W2023917616 @default.
- W2486356170 cites W2026146571 @default.
- W2486356170 cites W2027131382 @default.
- W2486356170 cites W2029193046 @default.
- W2486356170 cites W2033681603 @default.
- W2486356170 cites W2034619590 @default.
- W2486356170 cites W2035420335 @default.
- W2486356170 cites W2035757354 @default.
- W2486356170 cites W2038530539 @default.
- W2486356170 cites W2047135513 @default.
- W2486356170 cites W2048985510 @default.
- W2486356170 cites W2049477991 @default.
- W2486356170 cites W2049890508 @default.
- W2486356170 cites W2054000905 @default.
- W2486356170 cites W2058228207 @default.
- W2486356170 cites W2062768645 @default.
- W2486356170 cites W2063945805 @default.
- W2486356170 cites W2067719609 @default.
- W2486356170 cites W2069081926 @default.
- W2486356170 cites W2072612134 @default.
- W2486356170 cites W2075434681 @default.
- W2486356170 cites W2076187030 @default.
- W2486356170 cites W2082530573 @default.
- W2486356170 cites W2082650775 @default.
- W2486356170 cites W2086590564 @default.
- W2486356170 cites W2092645079 @default.
- W2486356170 cites W2096081051 @default.
- W2486356170 cites W2103039991 @default.
- W2486356170 cites W2110993073 @default.
- W2486356170 cites W2116281705 @default.
- W2486356170 cites W2123370797 @default.
- W2486356170 cites W2124213024 @default.
- W2486356170 cites W2128919738 @default.
- W2486356170 cites W2131415092 @default.
- W2486356170 cites W2131579749 @default.
- W2486356170 cites W2133408673 @default.
- W2486356170 cites W2144655298 @default.
- W2486356170 cites W2145864210 @default.
- W2486356170 cites W2146481987 @default.
- W2486356170 cites W2146934542 @default.
- W2486356170 cites W2162163433 @default.
- W2486356170 cites W2164758581 @default.
- W2486356170 cites W2166149223 @default.
- W2486356170 cites W2168785008 @default.
- W2486356170 cites W2313494153 @default.
- W2486356170 cites W2315317977 @default.
- W2486356170 cites W3124718557 @default.
- W2486356170 cites W4211197263 @default.
- W2486356170 cites W4256463441 @default.
- W2486356170 doi "https://doi.org/10.1016/j.jcms.2016.07.010" @default.
- W2486356170 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5026604" @default.
- W2486356170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27519661" @default.
- W2486356170 hasPublicationYear "2016" @default.
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