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- W2486459891 abstract "Abstract Although inherited hematopoietic malignancies have been reported clinically since the early twentieth century, the molecular basis for these diseases has only recently begun to be elucidated. Growing utilization of next-generation sequencing technologies has facilitated the rapid discovery of an increasing number of recognizable heritable hematopoietic malignancy syndromes while also deepening the field’s understanding of the molecular mechanisms that underlie these syndromes. Because individuals with inherited hematopoietic malignancies continue to be underdiagnosed and are increasingly likely to be encountered in clinical practice, clinicians need to have a high index of suspicion and be aware of the described syndromes. Here, we present the methods we use to identify, test, and manage individuals and families suspected of having a hereditary myeloid malignancy syndrome. Finally, we address the areas of ongoing research in the field and encourage clinicians and researchers to contribute and collaborate." @default.
- W2486459891 created "2016-08-23" @default.
- W2486459891 creator A5017604098 @default.
- W2486459891 creator A5065240782 @default.
- W2486459891 date "2016-10-06" @default.
- W2486459891 modified "2023-10-16" @default.
- W2486459891 title "How I diagnose and manage individuals at risk for inherited myeloid malignancies" @default.
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- W2486459891 doi "https://doi.org/10.1182/blood-2016-05-670240" @default.
- W2486459891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27471235" @default.
- W2486459891 hasPublicationYear "2016" @default.
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