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- W2487488664 abstract "INTRODUCTIONThe prevalence of mitral valve disease, especially mitral regurgitation (MR), is increasing. Despite significant gains in theeradication of rheumatic fever, rheumatic mitral stenosis (MS)remains a significant problem in underdeveloped countries. Inaddition to the increased incidence of degenerative mitral valvedisease due to the aging population, the growing congestiveheart failure epidemic has led to further increase in the proportion of patients with severe MR. The emergence of newpercutaneous technologies for mitral valve disease has generated great interest in the interventional community. Althoughpercutaneous balloon mitral valvuloplasty (BMV) is a wellestablished technique, the skill set necessary for this procedureremains critical to the well-rounded structural heart diseaseinterventionalist. This chapter reviews the indications andtechniques for percutaneous therapies for mitral valve disease.PERCUTANEOUS TREATMENT OF MITRALSTENOSISFundamentals and Anatomic ConsiderationsEtiologyThe most common cause of MS is rheumatic heart disease. Lesscommonly, congenital MS may be detected in children. Rarely,MS is a result of collagen vascular disease, mucopolysaccharidoses, amyloid deposits, or is drug-induced. In rheumaticmitral valve disease, fusion of the mitral valve apparatus mayoccur in the commissures, the cusps, or the chordae tendinae.While the majority of patients have a combination of the above,30% of patients have isolated commissural thickening, 15%have thickening of the cusps only, and 10% have only chordalthickening. Generally, the mitral cusps thicken at the edges andfuse at the commissures, while the chordae thicken, shorten,and fuse. This leads to a funnel-shaped valve with reducedleaflet mobility and a fish-mouth shaped orifice (Fig. 43.1). Ifthe commissures are predominantly involved, this leads mainlyto MS. Isolated thickening and shortening of the chordae resultsmainly in MR; however, if the cusps are thickened and adherent, so they cannot adequately open or close, a combination ofMS and regurgitation occurs." @default.
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- W2487488664 date "2010-08-24" @default.
- W2487488664 modified "2023-09-23" @default.
- W2487488664 title "Percutaneous therapies for mitral valve disease" @default.
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- W2487488664 doi "https://doi.org/10.3109/9780203093047-94" @default.
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