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- W2487673357 abstract "The issue whether hemochromatosis heterozygotes develop disease-related morbidity is controversial. Because iron is the source of the organ damage in hemochromatosis, heterozygotes would have to become iron loaded for complications to occur. By definition, heterozygotes have one-half of the hemochromatosis genotype, possessing one mutant and one wild-type allele. Does the presence of one-half of the hemochromatosis gene product result in the expression of one-half of the homozygous phenotype? Most importantly, do hemochromatosis heterozygotes develop disease-related morbidity?" @default.
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- W2487673357 date "2000-01-13" @default.
- W2487673357 modified "2023-10-16" @default.
- W2487673357 title "The iron phenotype of hemochromatosis heterozygotes" @default.
- W2487673357 doi "https://doi.org/10.1017/cbo9780511666476.040" @default.
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