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- W2487978459 abstract "Abstract This book is focused on new treatments that target the neurobiological abnormalities that have been detected in neurodevelopmental disorders. We have chosen to focus on 12 disorders because they represent either single gene disorders or complex disorders with both genetic and environmental factors working together to create a neurodevelopmental disorder. Some of the disorders are common, such as ADHD or autism spectrum disorder (ASD), and some are rare, such as Angelman syndrome. However, there are remarkable commonalities in their mechanisms of dysfunction, including oxidative stress, mitochondrial dysfunction, GABA and glutamate imbalances, and synaptic plasticity deficits that touch most of these disorders. We can learn from what neurodevelopmental mechanisms they share and see how these mechanisms can be targets for effective treatment. The development of one targeted treatment for one disorder may help other disorders related through these shared mechanisms." @default.
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- W2487978459 date "2014-07-01" @default.
- W2487978459 modified "2023-10-18" @default.
- W2487978459 title "Overview of Neurodevelopmental Processes and the Assessment of Patients with Neurodevelopmental Disorders" @default.
- W2487978459 doi "https://doi.org/10.1093/med/9780199937806.003.0001" @default.
- W2487978459 hasPublicationYear "2014" @default.
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